Results 21 to 30 of about 2,929 (132)
Journal of Chemical Technology &Biotechnology, EarlyView.Abstract BACKGROUND Efficient manufacturing of complex biopharmaceuticals increasingly relies on innovative downstream processing strategies. Membrane chromatography offers a promising alternative to resin‐based systems by enabling high‐throughput separations at elevated flow rates. Typically used in flow‐through mode, its industrial applications range
Jan Hedrich +6 more
wiley +1 more source
Hosting the plant cells in vitro : recent trends in bioreactors [PDF]
, 2013 Biotechnological production of high-value metabolites and therapeutic proteins by plant in vitro systems has been considered as an attractive alternative of classical technologies.
Eibl-Schindler, Regine +2 more
core +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 2, March 2026.ABSTRACT Microbial exopolysaccharides (EPS) represent a diverse class of biopolymers holding considerable promise as functional food ingredients. This review analyzes the dual function of microbial EPS as a candidate for prebiotic agents and techno‐functional additives.
Md. Abdur Razzak +7 more
wiley +1 more source
Process Systems Engineering in Precision Medicine: Opportunities in Autologous CAR‐T Therapy
Engineering in Life Sciences, Volume 26, Issue 2, February 2026.ABSTRACT Autologous chimeric antigen receptor (CAR)‐T therapies have given hope to many cancer patients whose other lines of treatment have failed. Unfortunately, limited manufacturing capability has resulted in many patients dying while on a waitlist.
B. Wayne Bequette
wiley +1 more source
Advanced Science, Volume 12, Issue 48, December 29, 2025.Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon +8 more
wiley +1 more source
Chlamydia trachomatis Genital Tract Infections: When Host Immune Response and the Microbiome Collide [PDF]
, 2016 © 2016 Genital infections with Chlamydia trachomatis continue to be a major health problem worldwide. While some individuals clear their infection (presumed to be the result of an effective Th1/interferon-γ response), others develop chronic infections ...
Hocking, JS +3 more
core +1 more source
Food Bioengineering, Volume 4, Issue 4, Page 589-611, December 2025.ABSTRACT Artificial intelligence (AI) has emerged as a paradigm‐shifting force in enzyme engineering, enabling data‐driven prediction of catalytic activity, stability, and substrate specificity. By integrating large‐scale datasets from structured databases (e.g., PDB, BRENDA) and high‐throughput experimentation (e.g., deep mutational scanning ...
Xiafeng Lu +11 more
wiley +1 more source
Bioorthogonal Strategy for Bioprocessing of Specific-Site-Functionalized Enveloped Influenza-Virus-Like Particles [PDF]
, 2016 Virus-like particles (VLPs) constitute a promising platform in vaccine development and targeted drug delivery. To date, most applications use simple nonenveloped VLPs as human papillomavirus or hepatitis B vaccines, even though the envelope is known to ...
, +10 more
core +3 more sources
Artificial intelligence‐driven anticancer peptide discovery
iMetaOmics, Volume 2, Issue 4, December 2025.This review systematically summarized 68 artificial intelligence (AI) models for anticancer peptide (ACP) screening and presented a comprehensive AI‐based framework. The framework consists of six components: data collection and organization, feature extraction, model construction, interpretability analysis, experimental validation, and integration with
Junrui Wu +20 more
wiley +1 more source
A Novel Methodology for Isolating Broadly Neutralizing HIV-1 Human Monoclonal Antibodies [PDF]
, 2013 also published in AIDS Research and Human Retroviruses. November 2013, 29(11): A-53.
Li, J, Shao, Y, Sun, Z, Zhang, M
core +4 more sources