Results 91 to 100 of about 1,560,419 (396)
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Plant-produced viral bovine vaccines: What happened during the last ten years? [PDF]
, 2015 Vaccination has proved to be an efficient strategy to deal with viral infections in both human and animal species. However, protection of cattle against viral infections is still a major concern in veterinary science.
Dus Santos, María José +3 more
core +1 more source
Development of Robust Freeze-Drying Process for Long-Term Stability of rVSV-SARS-CoV-2 Vaccine
VirusesThe thermostability of vaccines, particularly enveloped viral vectored vaccines, remains a challenge to their delivery wherever needed. The freeze-drying of viral vectored vaccines is a promising approach but remains challenging due to the water removal ...
MD Faizul Hussain Khan +3 more
doaj +1 more source
Journal of Advanced Veterinary and Animal Research, 2016 Objective: Caprine arthritis encephalitis (CAE) infection is existing worldwide causing economic loss in goat production. This work was conducted to investigate the prevalence of CAE in local and foreign goat breeds and sheep in different localities in ...
Wegdan Hassan Ali +10 more
doaj +1 more source
Universal Single-Dose Vaccination against Hepatitis A in Children in a Region of High Endemicity
Vaccines, 2020 Since August 2012, universal single-dose vaccination in children aged at least three years has been implemented in the Republic of Tuva, which was previously the region most affected by hepatitis A in Russia.
Mikhail I. Mikhailov +11 more
doaj +1 more source
Spin models inferred from patient data faithfully describe HIV fitness landscapes and enable rational vaccine design [PDF]
, 2013 Mutational escape from vaccine induced immune responses has thwarted the development of a successful vaccine against AIDS, whose causative agent is HIV, a highly mutable virus. Knowing the virus' fitness as a function of its proteomic sequence can enable rational design of potent vaccines, as this information can focus vaccine induced immune responses ...
arxiv +1 more source
Molecular Oncology, EarlyView.CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan +6 more
wiley +1 more source
Impact of inactivated poliovirus vaccine on mucosal immunity: implications for the polio eradication endgame. [PDF]
, 2015 The polio eradication endgame aims to bring transmission of all polioviruses to a halt. To achieve this aim, it is essential to block viral replication in individuals via induction of a robust mucosal immune response. Although it has long been recognized
Anis E +16 more
core +3 more sources
Production- and Purification-Relevant Properties of Human and Murine Cytomegalovirus
Viruses, 2021 There is a large unmet need for a prophylactic vaccine against human cytomegalovirus (HCMV) to combat the ubiquitous infection that is ongoing with this pathogen.
Sanda Ravlić +4 more
doaj +1 more source
An analysis of vaccine-related sentiments from development to deployment of COVID-19 vaccines [PDF]
arXiv, 2023 Anti-vaccine sentiments have been well-known and reported throughout the history of viral outbreaks and vaccination programmes. The COVID-19 pandemic had fear and uncertainty about vaccines which has been well expressed on social media platforms such as Twitter.
arxiv