Results 51 to 60 of about 2,924,139 (391)

Transcriptional Profiling of STAT1 Gain-of-Function Reveals Common and Mutation-Specific Fingerprints

Frontiers in Immunology, 2021
STAT1 gain-of-function (GOF) is a primary immunodeficiency typically characterized by chronic mucocutaneous candidiasis (CMC), recurrent respiratory infections, and autoimmunity.
Simone Giovannozzi, Simone Giovannozzi, Jonas Demeulemeester, Jonas Demeulemeester, Rik Schrijvers, Rik Gijsbers, Rik Gijsbers   +6 more
doaj   +1 more source

A Novel Unsupervised Method to Identify Genes Important in the Anti-viral Response: Application to Interferon/Ribavirin in Hepatitis C Patients [PDF]

, 2007
Background: Treating hepatitis C with interferon/ribavirin results in a varied response in terms of decrease in viral titer and ultimate outcome. Marked responders have a sharp decline in viral titer within a few days of treatment initiation, whereas in ...
A Hartnell, A Jail, A Schoenemeyer, Abdus S. Wahed, AI Su, AU Neumann, B Dong, BJ Barnes, C Oetke, C Sanda, CE Samuel, CL Johnson, E Tahara Jr, F Pazos, GW Snedecor, H Nguyen, H Tan, H Yang, J Gertz, Jia Li, John E. Tavis, K Honda, K Li, K Okochi, KA Fitzgerald, KJ Helbig, Leonid I. Brodsky, Milton W. Taylor, MJ de Veer, MP Manns, MW Fried, MW Fried, MW Taylor, MW Taylor, O Alter, R Sumpter Jr, S Zeuzem, SD Der, SD Desai, Sebastian Fugmann, SJ Hadziyannis, T Cox, Takuma Tsukahara, TK van den Berg, W Lim, X Ji   +45 more
core   +8 more sources

Current State of the Streptococcus pneumoniae Capsular Typing Problem

Антибиотики и Химиотерапия, 2022
Diseases caused by Streptococcus pneumoniae are a serious medical and social problem for healthcare systems of all leading countries around the globe.
Yu. A. Zakharova, V. G. Akimkin, E. V. Nikitina, I. A. Ivashchenko, E. V. Bolgarova, E. V. Aleksandrova, S. M. Skripkovskaya   +6 more
doaj   +1 more source

The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells. [PDF]

, 2015
Lentiviral vectors designed for the treatment of the hemoglobinopathies require the inclusion of regulatory and strong enhancer elements to achieve sufficient expression of the β-globin transgene.
Baldwin, Kismet M, Campo-Fernandez, Beatriz, Cooper, Aaron R, Hoban, Megan D, Hollis, Roger P, Kaufman, Michael L, Kohn, Donald B, Lumaquin, Dianne, Romero, Zulema, Senadheera, Shantha, Urbinati, Fabrizia, Wang, Xiaoyan, Wherley, Jennifer   +12 more
core   +4 more sources

Uranotaenia unguiculata Edwards, 1913 are attracted to sound, feed on amphibians, and are infected with multiple viruses

Parasites & Vectors, 2018
Background Uranotaenia unguiculata Edwards, 1913 is a species of mosquito (Diptera: Culicidae) native to central Europe. Recently a novel lineage of the West Nile virus (WNV-lineage 4c) was identified in pools of adult female Ur. unguiculata. To increase
Jeremy V. Camp, Tamás Bakonyi, Zoltán Soltész, Thomas Zechmeister, Norbert Nowotny   +4 more
doaj   +1 more source

Antibody prevalence to avian influenza virus subtypes H5, H7 and H9 in falcons, captive and wild birds, United Arab Emirates, 2003–2006

Veterinary Medicine and Science, 2023
Background Avian influenza viruses (AIV) may cause enormous economic losses in the poultry industry and sporadically severe disease in humans. Falconry is a tradition of great importance in the Arabian Peninsula.
Nicola Jöstl, Pia Weidinger, Helga Lussy, Tom A. Bailey, Sunitha Joseph, Sean McKeown, Declan O`Donovan, Xiangdong Li, Norbert Nowotny   +8 more
doaj   +1 more source

Belgian Anopheles plumbeus Mosquitoes Are Competent for Japanese Encephalitis Virus and Readily Feed on Pigs, Suggesting a High Vectorial Capacity

Microorganisms, 2023
Anopheles plumbeus, a day-active mosquito known to feed aggressively on humans, was reported as a nuisance species near an abandoned pigsty in Belgium.
Claudia Van den Eynde, Charlotte Sohier, Severine Matthijs, Nick De Regge   +3 more
doaj   +1 more source

Wolbachia versus dengue: Evolutionary forecasts. [PDF]

, 2013
A novel form of biological control is being applied to the dengue virus. The agent is the maternally transmitted bacterium Wolbachia, naturally absent from the main dengue vector, the mosquito Aedes aegypti.
Bull, James J, Turelli, Michael
core   +1 more source

Establishment of a Parvovirus B19 NS1-Expressing Recombinant Adenoviral Vector for Killing Megakaryocytic Leukemia Cells

Viruses, 2019
Adenoviral viral vectors have been widely used for gene-based therapeutics, but commonly used serotype 5 shows poor transduction efficiency into hematopoietic cells.
Peng Xu, Xiaomei Wang, Yi Li, Jianming Qiu   +3 more
doaj   +1 more source

Relevant Day/Night Temperatures Simulating Belgian Summer Conditions Reduce Japanese Encephalitis Virus Dissemination and Transmission in Belgian Field-Collected Culex pipiens Mosquitoes

Viruses, 2023
Japanese encephalitis virus (JEV), a zoonotic mosquito-borne Flavivirus, can be considered an emerging infectious disease. Therefore, vector competence studies with indigenous mosquitoes from regions where JEV is not yet endemic are of great importance ...
Claudia Van den Eynde, Charlotte Sohier, Severine Matthijs, Nick De Regge   +3 more
doaj   +1 more source