Results 51 to 60 of about 2,747,170 (398)
Is Viral Vector Gene Delivery More Effective Using Biomaterials?
Advanced Healthcare Materials, 2020 Gene delivery has been extensively investigated for introducing foreign genetic material into cells to promote expression of therapeutic proteins or to silence relevant genes.
Yi Wang +7 more
semanticscholar +1 more source
Analiz Riska Zdorovʹû, 2021 At present it is impossible to develop epidemiologic surveillance and control over any infection regarding studies on dynamics of morbidity, seasonality and periodicity without using mathematical modeling techniques.
I.V. Feldblium +7 more
doaj +1 more source
The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells. [PDF]
, 2015 Lentiviral vectors designed for the treatment of the hemoglobinopathies require the inclusion of regulatory and strong enhancer elements to achieve sufficient expression of the β-globin transgene.
Baldwin, Kismet M +12 more
core +4 more sources
Viruses, 2019 Adenoviral viral vectors have been widely used for gene-based therapeutics, but commonly used serotype 5 shows poor transduction efficiency into hematopoietic cells.
Peng Xu +3 more
doaj +1 more source
Microorganisms, 2023 Anopheles plumbeus, a day-active mosquito known to feed aggressively on humans, was reported as a nuisance species near an abandoned pigsty in Belgium.
Claudia Van den Eynde +3 more
doaj +1 more source
Gene Targeting with Viral Vectors
Molecular Therapy, 2005 Genetic manipulation of cells for scientific and therapeutic goals can be achieved by both gene-addition and gene-targeting methods. Gene targeting precisely alters a gene in its natural chromosome location, providing distinct advantages over gene-addition approaches.
Paul C. Hendrie, David W. Russell
openaire +3 more sources
Parasites & Vectors, 2015 Background Biting midges of the genus Culicoides Latreille, 1809 (Diptera: Ceratopogonidae) cause a significant biting nuisance to equines and are responsible for the biological transmission of African horse sickness virus (AHSV).
Tiffany Baker +6 more
doaj +1 more source
Viruses, 2023 Japanese encephalitis virus (JEV), a zoonotic mosquito-borne Flavivirus, can be considered an emerging infectious disease. Therefore, vector competence studies with indigenous mosquitoes from regions where JEV is not yet endemic are of great importance ...
Claudia Van den Eynde +3 more
doaj +1 more source
Rapid and efficient stable gene transfer to mesenchymal stromal cells using a modified foamy virus vector [PDF]
, 2016 Mesenchymal stromal cells (MSCs) hold great promise for regenerative medicine. Stable ex vivo gene transfer to MSCs could improve the outcome and scope of MSC therapy, but current vectors require multiple rounds of transduction, involve genotoxic viral ...
Dazzi, F +7 more
core +2 more sources
Viral vectors for vaccine applications
Clinical and Experimental Vaccine Research, 2013 Traditional approach of inactivated or live-attenuated vaccine immunization has resulted in impressive success in the reduction and control of infectious disease outbreaks. However, many pathogens remain less amenable to deal with the traditional vaccine strategies, and more appropriate vaccine strategy is in need.
Jun Chang, Young Joo Choi
openaire +3 more sources