Results 31 to 40 of about 285,022 (264)
Launching the Leadership Academy
In April 2010, the Virginia Library Association (VLA) launched the Virginia Library Leadership Academy (VALLA), the first-ever leadership development training program of its kind for staff in Virginia libraries.
Elizabeth Hensley
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Virginia Institute of Genealogy Research
An innovative partnership between the Virginia Library Association and the Virginia Genealogical Society made a scholarship available for a VLA member to attend the annual Virginia Institute of Genealogical Research this past August.
Linda Derrer
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Two Novel Energy Crops: Sida hermaphrodita (L.) Rusby and Silphium perfoliatum L.—State of Knowledge
Current global temperature increases resulting from human activity threaten many ecosystems and societies, and have led to international and national policy commitments that aim to reduce greenhouse gas emissions.
Laura Cumplido-Marin +9 more
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The study, diverging from current critical discourse on Virginia Woolf as eccentric author, sets out expressly to look at Woolf as enigmatic text. In so doing, it explores largely untapped Woolf terrain.
Adrian A. Husain
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We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Natural Resources of Virginia and West Virginia [PDF]
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