Results 141 to 150 of about 104,970 (255)

Hepatitis B virus infection with high HBsAg and undetectable DNA levels in untreated blood donors: Viral mechanisms and transfusion safety implications

Transfusion, EarlyView.
Abstract Background Blood donor screening occasionally identifies individuals with high HBV surface antigen (HBsAg) levels despite undetectable or extremely low HBV DNA. Molecular basis and transfusion risk of this discordant profile remain unclear. Study Design and Methods Seventy‐five blood donors with HBsAg >100 IU/mL and undetectable or very low ...
Maelenn Païline Delcourt, Marion Vermeulen, Aneta Kopacz, Manuela Miletic, Andrew Saville, Christoph Niederhauser, Jean‐Michel Pawlotsky, Syria Laperche, Daniel Candotti   +8 more
wiley   +1 more source

Cryo-EM study of bacteriophage N4 virion RNA polymerase. [PDF]

J Bacteriol
Narwal M, Shin Y, Murakami KS.
europepmc   +1 more source

Natural Infection by Toscana Virus and Other Phleboviruses in Wild Sand Flies From Spain: Prevalence, Genetic Characterization and Tripartite Interactions With Leishmania infantum and Wolbachia

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Toscana virus (TOSV) and Leishmania species are sand fly‐borne pathogens that pose a significant public health threat and an increasing risk of exposure in Europe. The objective of this study was to identify the phleboviruses circulating in an area endemic for sand fly‐borne pathogens and to estimate infection prevalence in wild ...
Andrés Torres‐Llamas, Antonio Sampedro, Victoriano Díaz‐Sáez, Manuel Morales‐Yuste, Javier Rodríguez‐Granger, Irene Pedrosa‐Corral, José María Navarro‐Marí, Francisco Morillas‐Márquez, Joaquina Martín‐Sánchez   +8 more
wiley   +1 more source

Impact of COVID-19 Vaccine Type on the Efficacy and Safety of Nivolumab in Patients With Metastatic Non-small-cell Lung Cancer: A Multicenter Study. [PDF]

In Vivo
Karabuga B, Büyükkör M, Karaçin C, Karabuga EK, Yildiz S, Güneysu GG, Akgüner G, Uzundere FK, Arslan A, Davarci SE, Urakçi Z, Sütçüoğlu O, Yildirim ÖA, Karadurmuş N, Ergün Y.   +14 more
europepmc   +1 more source

Polycationic Peptide Engineering of Phage Endolysins Expands Host Range and Enhances Antibacterial and Antibiofilm Activities Against Bacillus Species

Biotechnology and Bioengineering, Volume 123, Issue 10, Page 2788-2801, October 2026.
ABSTRACT The exponential rise in antimicrobial resistance has highlighted the urgent need for the development of alternative antibacterial strategies, including phage‐derived and engineered protein agents such as endolysins and artilysins. In this study, we report the rational design, expression, and functional characterization of novel artilysins ...
Farhat Ansari, Tarushi, Vandan Nagar
wiley   +1 more source

Unveiling the Structural and Mechanical Diversity of SARS-CoV-2 Variants Using Atomic Force Microscopy. [PDF]

ACS Appl Mater Interfaces
Sziklai D, Budavári B, Kiss B, Herényi L, Kis Z, Pályi B, Kellermayer M.   +6 more
europepmc   +1 more source

Genomic and Phenotypic Characterization of Two Novel Enterobacter Phages With EDTA‐Enhanced Antibiofilm Activity

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Two novel lytic Enterobacter phages, HHH and RZH, displayed targeted antibiofilm activity against MDR Enterobacter cloacae complex biofilms when combined with EDTA. Activity was strongest within a narrow low‐millimolar EDTA window, reducing biofilm biomass and viable burden, while higher EDTA concentrations shifted the interaction towards antagonism ...
Kashif Haq, Zac Newland‐Smith, Martin Figgit, David Lee, Kwabena Duedu   +4 more
wiley   +1 more source

Disentangling production and persistence of extracellular virions in grassland soils with SIP-viromics. [PDF]

mSystems
Trubl G, Roux S, Kellom M, Vyshenska D, Tomatsu A, Singh K, Kimbrel JA, Eloe-Fadrosh E, Malmstrom RR, Pett-Ridge J, Blazewicz SJ.   +10 more
europepmc   +1 more source

Quantifying Viral Lysis in Microalgae Using Cell‐Free rRNA

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Cell‐free ribosomal RNA (rRNA) dissolved in seawater provides a quantitative proxy for viral lysis in microeukaryotic phytoplankton. Incubation experiments with two distinct host–virus systems revealed marked increases in cell‐free rRNA production per cell, a proxy for lytic mortality, reaching up to 46‐ and 302‐fold relative to noninfected controls ...
Saki Kikuya, Yuji Tomaru, Keizo Nagasaki, Daichi Morimoto, Yuki Yamagishi, Hiroyuki Ogata, Hisashi Endo   +6 more
wiley   +1 more source

Plant-Derived Anti-TMV Metabolites: Mechanisms, Limitations and Future Perspectives. [PDF]

Viruses
Aslam MQ, Gao Z, Mohamed AS, El-Sayed SM, Yang W, Cheng L, Wu K, Li Y, Chen Y.   +8 more
europepmc   +1 more source