Results 81 to 90 of about 146,116 (296)
Mechanism of HIV-1 virion entrapment by tetherin. [PDF]
PLoS Pathogens, 2013 Tetherin, an interferon-inducible membrane protein, inhibits the release of nascent enveloped viral particles from the surface of infected cells. However, the mechanisms underlying virion retention have not yet been fully delineated.
Siddarth Venkatesh, Paul D Bieniasz
doaj +1 more source
Antiviral effects and mechanism of Qi pi pill against influenza viruses
Animal Models and Experimental Medicine, EarlyView.Qi pi pill presents anti‐influenza effect and inhibits viral replication in vitro by targeting both the viral RNA replication and the release of new viral particles. Furthermore, QPP modulates the production of proinflammatory cytokines induced by influenza infection in host cells.
Chengcheng Zhang +10 more
wiley +1 more source
RNA Polymerase in Mumps Virion [PDF]
Journal of Virology, 1974 Mumps virions of the Enders' strain were examined for polymerase activity in vitro. An RNA-dependent RNA polymerase was found to be associated with the virion. The general properties of the reaction appear to be similar to those described for other paramyxoviruses.
Robert L. Northrop +1 more
openaire +3 more sources
β-Coronaviruses exploit ESCRT for virion assembly and egress
mBioβ-Coronaviruses assemble at the endoplasmic reticulum-to-Golgi compartment and exit cells through the lysosomal trafficking pathway. However, the molecular mechanisms of virion assembly and egress are largely unknown. Here, we report that β-coronaviruses
Yuanyuan Zhang +5 more
doaj +1 more source
Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production
Journal of Biology, 2003 Background The retroviral Gag protein is the central player in the process of virion assembly at the plasma membrane, and is sufficient to induce the formation and release of virus-like particles.
De Camilli Pietro +6 more
doaj +1 more source
Comparison of the pathogenicity of multiple SARS‐CoV‐2 variants in mouse models
Animal Models and Experimental Medicine, EarlyView.We assessed the pathogenicity of various SARS‐CoV‐2 variants using two distinct mouse models. Our findings indicated that earlier variants, including WH‐09, Beta, and Delta, exhibited greater pathogenicity than later variants. Specifically, the Omicron variant demonstrated reduced pathogenicity, characterized by a shorter disease course and diminished ...
Qi Lv +12 more
wiley +1 more source
Angewandte Chemie, EarlyView.Die virale Bindung und Fusion stellen frühe Schritte in der Virusinfektion dar. Die oberflächenverstärkte Infrarotabsorptionsspektroskopie ermöglicht die markierungsfreie Beobachtung molekularer Prozesse während der Interaktion des Influenza‐A‐Virus mit einem Wirtszellmembranmodell und liefert chemische Auflösung zur Unterscheidung viraler Proteine ...
Amelie Teresa Heinen +4 more
wiley +1 more source
A functional link between the actin cytoskeleton and lipid rafts during budding of filamentous influenza virions [PDF]
, 2002 Morphogenesis of influenza virus is a poorly understood process that produces two types of enveloped virion: ∼100-nm spheres and similar diameter filaments that reach 20 μm in length.
Digard, Paul +5 more
core +1 more source
Virion Structure and Composition
, 2017 Extracellular virus consists of the viral genome surrounded by a protective coat of protein; the resulting nucleocapsid may be surrounded by an outer lipid envelope in which viral proteins are embedded. Viral proteins confer specificity as to the range and type of host cell that may be infected.
Burrell, Christopher J. +2 more
openaire +1 more source
5'-terminal structure of poliovirus polyribosomal RNA is pUp [PDF]
, 1976 Poliovirus RNA purified from virus-specific polyribosomes does not contain m7G in a 5'-5'-pyrophosphate linkage at its 5'-end. The only potential 5'-end found in ribonuclease digests of this RNA is pUp, which is present in a yield of 1 mole/mole of ...
Baltimore, David +2 more
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