Evaluation of Clinical and Immunological Markers for predicting Virological Failure in a HIV/AIDS treatment cohort in Busia, Kenya [PDF]
In resource-limited settings where viral load (VL) monitoring is scarce or unavailable, clinicians must use immunological and clinical criteria to define HIV virological treatment failure. This study examined the performance of World Health Organization (
A Calmy +30 more
core +44 more sources
Predictive factors associated with virological failure among adult patients living with HIV on first-line highly active antiretroviral therapy in Southeast Oromia, Ethiopia: a case-control study. [PDF]
Objectives The study aimed to identify the predictive factors associated with virological failure among adult patients living with HIV on first-line highly active antiretroviral therapy (HAART) in selected hospitals in Southeast Oromia, Ethiopia.Design A
Gedefa LK +4 more
europepmc +2 more sources
IntroductionHuman Immune deficiency Virus or Acquired Immune deficiency Syndrome (HIV/AIDS) is a pandemic affecting millions around the world. The 2020 the Joint United Nations Programme on HIV/AIDS report stated that the estimated number of people ...
Demeke Eshetu Andarge +2 more
doaj +2 more sources
Sustained virological response on second-line antiretroviral therapy following virological failure in HIV-infected patients in rural South Africa. [PDF]
OBJECTIVE: This study aims to describe the virological, immunological and clinical efficacy of protease inhibitor (PI)-based second-line antiretroviral therapy (ART) in rural South Africa.
Annelot F Schoffelen +5 more
doaj +1 more source
Magnitude and factors associated with virological failure among adults on first-line antiretroviral therapy in Dire Dawa, eastern Ethiopia: a retrospective chart review. [PDF]
Background First-line antiretroviral therapy failure reduces the benefits of the antiretroviral therapy (ART) program and could lead to regimen change to a more expensive second-line ART.
Dibaba KT +3 more
europepmc +2 more sources
Predicting Virologic Failure in an HIV Clinic [PDF]
Abstract Background . We sought to use data captured in the electronic health record (EHR) to develop and validate a prediction rule for virologic failure among patients being treated for infection with human immunodeficiency virus (HIV). Methods .
Gregory K, Robbins +6 more
openaire +2 more sources
Time to virological failure and its predictors among children receiving first-line antiretroviral treatment in selected public Hospitals, Eastern Ethiopia, 2022: A multicenter retrospective cohort study. [PDF]
Introduction: The World Health Organization recommends the viral load test as the preferred method for monitoring responses to antiretroviral treatment; however, this test is not widely available in developing countries.
Ibirahim MK +3 more
europepmc +2 more sources
Induction with lopinavir-based treatment followed by switch to nevirapine-based regimen versus non-nucleoside reverse transcriptase inhibitors-based treatment for first line antiretroviral therapy in HIV infected children three years and older. [PDF]
BACKGROUND:The World Health Organization recommends non-nucleoside reverse transcriptase inhibitors (NNRTIs)-based antiretroviral therapy (ART) for children three years and older.
Gerardo Alvarez-Uria +3 more
doaj +1 more source
Performance of Immunological Response in Predicting Virological Failure [PDF]
In HIV-infected individuals on antiretroviral therapy (ART), the decision on when to switch from first-line to second-line therapy is dictated by treatment failure, and this can be measured in three ways: clinically, immunologically, and virologically.
Nayana, Ingole +4 more
openaire +2 more sources
Incidence and predictors of virological failure among HIV infected children and adolescents receiving second-line antiretroviral therapy in Uganda, a retrospective study. [PDF]
Background In Uganda, 20% (19,073/94,579) of children and adolescents (0-19 years) living with HIV (CALHIV) were receiving second-line antiretroviral therapy (ART) by the end of March 2020.
Musiime-Mwase F +7 more
europepmc +2 more sources

