Results 41 to 50 of about 45,169 (292)

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

Virological efficacy of PI monotherapy for HIV-1 in clinical practice. [PDF]

, 2016
BACKGROUND: Clinical trials of PI monotherapy indicate that most participants maintain viral suppression and emergent protease resistance is rare.
Collier, D, Copas, AJ, El Bouzidi, K, Gupta, RK, Miller, RF, Nastouli, E   +5 more
core   +1 more source

Virological failure and associated factors among children receiving anti-retroviral therapy, Northwest Ethiopia.

PLoS ONE, 2021
BackgroundVirological failure is under-recognized issue among children living with human immunodeficiency virus in developing countries. This partly may lead to failure to achieve the global goal of 90-90-90 targets in most developing countries including
Biruk Bayleyegn, Zemene Demelash Kifle, Demeke Geremew   +2 more
doaj   +1 more source

Leveraging corona virus disease 2019 vaccination to promote hepatitis C screening

Hepatology Communications, EarlyView., 2022
Abstract Health care initiatives, such as hepatitis C virus (HCV) screening, have been greatly overshadowed by the corona virus disease 2019 (COVID‐19) pandemic. However, COVID‐19 vaccination programs also provide an opportunity to engage with a high volume of people in a health care setting.
Aaron Vanderhoff, David Smookler, Mia J. Biondi, Scott Enman, Tintin Fuliang, Sana Mahmood, Agustina Crespi, Maria Marquez, Rafique Van Uum, Lucy You, Brett Wolfson‐Stofko, Renee Logan, Erin LeDrew, Hemant Shah, Harry Janssen, Camelia Capraru, Elisa Venier, Jordan J. Feld   +17 more
wiley   +1 more source

Virological failure and associated factors among patients receiving anti-retroviral therapy in Ethiopia: A systematic review and meta-analysis. [PDF]

BMJ Open
Objective This study aimed to pool the prevalence of virological failure and associated factors.Design Systematic review and meta-analysis.Primary outcome measure Prevalence of virological failure.Secondary outcome measure Factors affecting virological ...
Aytenew TM, Asferie WN, Ejigu N, Birhane BM, Tiruneh YM, Kassaw A, Asnakew S, Legas G, Munie BM, Belay BM, Ewunetu M, Kefale D, Kebede SD.   +12 more
europepmc   +2 more sources

A Retrospective Survey of HIV Drug Resistance Among Patients 1 Year After Initiation of Antiretroviral Therapy at 4 Clinics in Malawi [PDF]

, 2012
In 2004, Malawi began scaling up its national antiretroviral therapy (ART) program. Because of limited treatment options, population-level surveillance of acquired human immunodeficiency virus drug resistance (HIVDR) is critical to ensuring long-term ...
Anthony Harries, Barth, Ben Chilima, Bennett, Bennett, Bethany L. Hedt, Carol Porter, Coetzee, Diane E. Bennett, Eddie Limbambala, Erik Schouten, George Bello, Hedt, Hosseinipour, Joep J. van Oosterhout, Johannessen, John Aberle-Grasse, Jordan, Kamoto, Kamya, Kouanfack, Koyalta, Kundai Moyo, Liu, Maldonado, Marcelin, Marconi, Michael R. Jordan, Mina Hosseinipour, Ministry of Health, Moses Massaquoi, Nellie Wadonda-Kabondo, Nzeyimana, Oyugi, Pillay, Puthanakit, Ralf Weigel, Storn Kabuluzi, Sungkanuparph, Wallis, Yu   +40 more
core   +2 more sources

Correlation of HIV-1 drug resistant mutations and virologic failure

Pan African Medical Journal, 2021
mutations are important by ensuring that the HIV-1 agent remains fit in the environment and evades drugs that are developed purposely to kill them. In Kenya, mutations conferring resistance to available ARVs have been reported in previous studies. However, there is a paucity of information on whether these previous studies have reported all mutations ...
Olipher Makwaga, David Hughes Mulama, John Muoma, Matilu Mwau   +3 more
openaire   +3 more sources

Long-Term Outcome of an HIV-Treatment Programme in Rural Africa: Viral Suppression despite Early Mortality

AIDS Research and Treatment, 2011
Objective. To define the long-term (2–4 years) clinical and virological outcome of an antiretroviral treatment (ART) programme in rural South Africa. Methods.
Roos E. Barth, Hugo A. Tempelman, Robert Moraba, Andy I. M. Hoepelman   +3 more
doaj   +1 more source

Magnitude and correlates of virological failure among adult HIV patients receiving PI based second line ART regimens in north western Tanzania; a case control study

BMC Infectious Diseases, 2019
Background With a growing access to free ART, switching of ART to second line regimen has also become common following failure of first line ART regimens.
Daniel W. Gunda, Semvua B. Kilonzo, Tarcisius Mtaki, Desderius M. Bernard, Samwel E. Kalluvya, Elichilia R. Shao   +5 more
doaj   +1 more source

The virological durability of first-line ART among HIV-positive adult patients in resource limited settings without virological monitoring: a retrospective analysis of DART trial data [PDF]

, 2017
BACKGROUND: Few low-income countries have virological monitoring widely available. We estimated the virological durability of first-line antiretroviral therapy (ART) after five years of follow-up among adult Ugandan and Zimbabwean patients in the DART ...
Chirara, M, DART Virology Group, ., Dolling, DI, Dunn, DT, Eram, D, Gilks, CF, Goodall, RL, Hakim, J, Kaleebu, P, Munderi, P, Nkurunziza, P, Pillay, D, Spyer, MJ, Tumukunde, D   +13 more
core   +6 more sources