Results 41 to 50 of about 1,729,369 (285)

HIV Virologic Failure among Patients with Persistent Low‐Level Viremia in Nairobi, Kenya: It Is Time to Review the >1000 Virologic Failure Threshold

BioMed Research International, 2023
Persistent low‐level viremia (PLLV) of 200‐999 copies/ml has been reported as a risk factor for HIV virologic failure (VF). This retrospective study was aimed at characterizing patients with PLLV, determining factors associated with VF, and determining the effect of regimen change.
Mirriam M. Nzivo, Cecilia N. Waruhiu, James M. Kang’ethe, Nancy L. M. Budambula   +3 more
openaire   +2 more sources

Factors Affecting Virological Failure in Children Receiving First-Line Antiretroviral Therapy in Ethiopian Healthcare Facilities: A Retrospective Analysis. [PDF]

Pediatric Health Med Ther
Mitiku Desalegn,1 Tewoderos Shitemaw,2 Mesfin Tesfaye,3 Genanew Kassie Getahun3 1Department of Anesthesia, College of Medicine and Health Science, Wachemo University, Hossana, Ethiopia; 2Menelik II Medical and Health Science College, Addis Ababa ...
Desalegn M, Shitemaw T, Tesfaye M, Getahun GK, Getahun GK.   +4 more
europepmc   +2 more sources

Challenges and Opportunities for the Implementation of Virological Testing in resource-limited settings [PDF]

, 2012
Though the advantages of routine virological monitoring for patients on anti-retroviral therapy have been established, cost and complexity limit its full implementation.
Bygrave, Helen, Nathan Ford, Teri Roberts, Fajardo, Emmanuel, Ford, Nathan, Emmanuel Fajardo, Roberts, Teri, Helen Bygrave   +7 more
core   +1 more source

Long-term virological suppression on first-line efavirenz + tenofovir + emtricitabine/lamivudine for HIV-1 [PDF]

, 2019
OBJECTIVES: Evaluate long-term rates of virological failure and treatment interruption for people living with HIV (PLWHIV) with viral suppression on first-line efavirenz + tenofovir disoproxil fumarate + emtricitabine/lamivudine (EFV + TDF + FTC/3TC ...
Long-Term Virological Suppression Working Group, .
core   +1 more source

Virological failure and associated factors among children receiving anti-retroviral therapy, Northwest Ethiopia.

PLoS ONE, 2021
BackgroundVirological failure is under-recognized issue among children living with human immunodeficiency virus in developing countries. This partly may lead to failure to achieve the global goal of 90-90-90 targets in most developing countries including
Biruk Bayleyegn, Zemene Demelash Kifle, Demeke Geremew   +2 more
doaj   +1 more source

Farnesyltransferase Enables Modular Assembly of Dual‐Functional Nanobody Conjugates for in Vivo Imaging of Inflammation

Angewandte Chemie, EarlyView.
A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy, Yoon Ho Lee, Ali Salehi Farid, Heydar Moravej, Sina Djafari Rouhani, Jennifer E. Rowley, Mohammad Rashidian, Mark D. Distefano   +7 more
wiley   +2 more sources

Long-Term Outcome of an HIV-Treatment Programme in Rural Africa: Viral Suppression despite Early Mortality

AIDS Research and Treatment, 2011
Objective. To define the long-term (2–4 years) clinical and virological outcome of an antiretroviral treatment (ART) programme in rural South Africa. Methods.
Roos E. Barth, Hugo A. Tempelman, Robert Moraba, Andy I. M. Hoepelman   +3 more
doaj   +1 more source

Magnitude and correlates of virological failure among adult HIV patients receiving PI based second line ART regimens in north western Tanzania; a case control study

BMC Infectious Diseases, 2019
Background With a growing access to free ART, switching of ART to second line regimen has also become common following failure of first line ART regimens.
Daniel W. Gunda, Semvua B. Kilonzo, Tarcisius Mtaki, Desderius M. Bernard, Samwel E. Kalluvya, Elichilia R. Shao   +5 more
doaj   +1 more source

Real-world prevalence of integrase inhibitor resistance and virological failure since adoption as guideline-preferred therapy. [PDF]

Drugs Context
Background: Limited data reporting real-world prevalence of integrase strand transfer inhibitor resistance (INSTI-R) in the USA are available because their recommendation as first-line treatment in 2017.
Januszka J, Drwiega E, Burgos R, Smith R, Badowski M.   +4 more
europepmc   +2 more sources

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source