Results 31 to 40 of about 1,729,369 (285)

Adherence to Antiretroviral Therapy and Virologic Failure

Medicine, 2016
The often cited need to achieve ≥95% (nearly perfect) adherence to antiretroviral therapy (ART) for successful virologic outcomes in HIV may present a barrier to initiation of therapy in the early stages of HIV. This meta-analysis synthesized 43 studies (27,905 participants) performed across >26 countries, to determine the relationship between cut-off ...
Bezabhe, Woldesellassie M., Chalmers, Leanne, Bereznicki, Luke R., Peterson, Gregory M.   +3 more
openaire   +2 more sources

Low‐level residual viremia and risk of virological failure [PDF]

Journal of the International AIDS Society, 2010
7‐11 November 2010, Tenth International Congress on Drug Therapy in HIV Infection, Glasgow ...
Cologni, G, Soavi, L, Leone, S, Valenti, D, Callegaro, A, Gregis, G, Suter, F, Maggiolo, F   +7 more
openaire   +1 more source

Virological failure of patients on maraviroc-based antiretroviral therapy [PDF]

Journal of Antimicrobial Chemotherapy, 2015
Abstract Objectives Virological failure (VF) in patients on maraviroc-based treatment has been associated with altered HIV tropism and resistance to maraviroc. This multicentre study aimed to characterize VF in patients treated with maraviroc. Methods
Stéphanie Raymond, Anne Maillard, Corinne Amiel, Gilles Peytavin, Mary Anne Trabaud, Delphine Desbois, Pantxika Bellecave, Constance Delaugerre, Cathia Soulie, Anne Geneviève Marcelin, Diane Descamps, Jacques Izopet, S. Reigadas, P. Bellecave, P. Pinson-Recordon, H. Fleury, B. Masquelier, A. Signori-Schmuck, P. Morand, L. Bocket, L. Mouna, P. André, J. C. Tardy, M. A. Trabaud, D. Descamps, C. Charpentier, G. Peytavin, F. Brun-Vézinet, S. Haim-Boukobza, A. M. Roques, C. Soulié, S. Lambert-Niclot, I. Malet, M. Wirden, S. Fourati, A. G. Marcelin, V. Calvez, P. Flandre, L. Assoumou, D. Costagliola, L. Morand-Joubert, C. Delaugerre, V. Schneider, C. Amiel, G. Giraudeau, A. Maillard, F. Nicot, J. Izopet   +47 more
openaire   +3 more sources

Treatment interruption and variation in tablet taking behaviour result in viral failure: a case-control study from Cape Town, South Africa. [PDF]

, 2011
BACKGROUND: Understanding of the impact of non-structured treatment interruption (TI) and variation in tablet-taking on failure of first-line antiretroviral therapy (ART) is limited in a resource-poor setting.
Orrell, Catherine, Lisa-Noelle Ncaca, Katharina Kranzer, Ncaca Lisa-Noelle, Orrell Catherine, Kranzer, Katharina, Ncaca, Lisa-Noelle, Catherine Orrell, Kranzer Katharina   +8 more
core   +1 more source

Magnitude and Determinants of Virological Failure Among Patients >15 Years on Anti-Retroviral Therapy in Rural Lesotho Between 2015 and 2019 – A Retrospective Cohort Study

HIV/AIDS: Research and Palliative Care, 2023
Thabo Ishmael Lejone,1,2 Ozayr Mahomed1 1SolidarMed, Lesotho, South Africa; 2Discipline of Public Health Medicine, University of KwaZulu Natal, Durban, South AfricaCorrespondence: Ozayr Mahomed, Howard College, University of KwaZulu Natal, 227 George ...
Lejone TI, Mahomed O
doaj  

Management of Virologic Failure and HIV Drug Resistance

Infectious Disease Clinics of North America, 2019
Approximately 20% of people with HIV in the United States prescribed antiretroviral therapy are not virally suppressed. Thus, optimal management of virologic failure has a critical role in the ability to improve viral suppression rates to improve long-term health outcomes for those infected and to achieve epidemic control.
Suzanne M, McCluskey, Mark J, Siedner, Vincent C, Marconi   +2 more
openaire   +3 more sources

Drug resistance in HIV patients with virological failure or slow virological response to antiretroviral therapy in Ethiopia [PDF]

BMC Infectious Diseases, 2014
The ongoing scale-up of antiretroviral therapy (ART) in sub-Saharan Africa has prompted the interest in surveillance of transmitted and acquired HIV drug resistance. Resistance data on virological failure and mutations in HIV infected populations initiating treatment in sub-Saharan Africa is sparse.HIV viral load (VL) and resistance mutations pre-ART ...
Abdissa, Alemseged, Yilma, Daniel, Fonager, Jannik, Audelin, Anne M, Christensen, Lone H, Olsen, Mette Frahm, Tesfaye, Markos, Kæstel, Pernille, Girma, Tsinuel, Aseffa, Abraham, Friis, Henrik, Pedersen, Court, Andersen, Åse B   +12 more
openaire   +5 more sources

Incidence and predictors of virological failure among adult HIV patients on first-line antiretroviral therapy in Amhara regional referral hospitals; Ethiopia: a retrospective follow-up study

BMC Infectious Diseases, 2020
Background Although the United Nations program on HIV/AIDS 90–90-90-targets recommends achieving 90% of viral suppression for patients on first-line antiretroviral therapy by 2020, virological failure is still high and it remains a global public health ...
Chilot Desta Agegnehu, Mehari Woldemariam Merid, Melaku Kindie Yenit   +2 more
doaj   +1 more source

Detecting virological failure in HIV-infected Tanzanian children

South African Medical Journal, 2014
The performance of clinical and immunological criteria to predict virological failure in HIV-infected children receiving antiretroviral therapy (ART) is not well documented.To determine the validity of clinical and immunological monitoring in detecting virological failure in children on ART.A total of 218 children were included in the study.
Mgelea, E M, Kisenge, R, Aboud, S
openaire   +5 more sources

Accuracy of WHO CD4 cell count criteria for virological failure of antiretroviral therapy [PDF]

, 2009
OBJECTIVES: To examine the accuracy of the World Health Organization immunological criteria for virological failure of antiretroviral treatment. METHODS: Analysis of 10 treatment programmes in Africa and South America that monitor both CD4 cell counts ...
Sprinz, Eduardo, Keiser, Olivia, Egger, Matthias, MacPhail, Patrick, Boulle, Andrew, Dabis, François, Schechter, Mauro, Wood, Robin   +7 more
core   +1 more source