Background/objective: The World Health Organization (WHO) recommends routine assessment of antiretroviral treatment outcomes to detect treatment failure early and prevent the development of drug resistance. The aim of this study was to describe treatment
Nwaiwu O +3 more
doaj
Virological failure in a pediatric cohort on a dolutegravir based regimen: a retrospective study in northwest Ethiopia, 2017-2023. [PDF]
Zewdu WS +5 more
europepmc +1 more source
Hepatitis B Virus RNA Predicts Hepatocellular Carcinoma Despite Viral Suppression
Serum HBV RNA levels at viral suppression predict HCC development in nucleos(t)ide analogue‐treated patients with chronic hepatitis B, outperforming Hepatitis B core‐related antigen alone. ABSTRACT Background Despite achieving undetectable hepatitis B virus (HBV) DNA levels with nucleos(t)ide analogue (NA) therapy, patients with chronic hepatitis B ...
Takashi Kumada +6 more
wiley +1 more source
Virological failure and risk factors among people living with HIV taking second-line ART in Addis Ababa, Ethiopia. [PDF]
Feyissa BB +4 more
europepmc +1 more source
Cutaneous and non‐cutaneous diseases due to Mycoplasma pneumoniae in children
Summary Mycoplasma pneumoniae (MP) is a common pathogen responsible for diverse infections in children and adolescents, primarily affecting the respiratory tract. Besides causing atypical pneumonia, MP can also lead to extrapulmonary manifestations, including mucocutaneous, hematological, neurological, cardiac, and gastrointestinal symptoms.
Hanna Lindemann +5 more
wiley +1 more source
Risk Factors Associated with Virological Failure in HIV Patients with Low Level Viremia: A Retrospective Study. [PDF]
Yang K +6 more
europepmc +1 more source
Retreatment of Direct Acting Agents (DAAs) After Initial DAA Failure in Hepatitis C Patients
ABSTRACT Background and Aims Glecaprevir/pibrentasvir (GLE/PIB) and sofosbuvir/ledipasvir (SOF/LDV) are widely used as first‐line direct‐acting antiviral (DAA) regimens for chronic hepatitis C, achieving high virus eradication rates. However, a small proportion of patients experience treatment failure, and the optimal retreatment strategies for such ...
Nobuharu Tamaki +10 more
wiley +1 more source
The post‐to pretreatment serum CXCL10 ratio was independently associated with short‐term liver function outcome following HCV eradication in cirrhotic patients. ABSTRACT Aim The prognostic value of serum C‐X‐C motif chemokine ligand 10 (CXCL10) levels for liver function was investigated in hepatitis C virus (HCV)–infected patients with compensated or ...
Takanori Suzuki +20 more
wiley +1 more source
Field performance and cost-effectiveness of a point-of-care triage test for HIV virological failure in Southern Africa. [PDF]
Saura-Lázaro A +14 more
europepmc +1 more source
In a population‐based cohort in Japan, HBV reactivation‐related events were observed after HBsAg seroclearance, including one virologically confirmed hepatic flare occurring spontaneously without chemotherapy or immunosuppression. These findings indicate that HBsAg seroclearance does not always represent complete viral eradication, supporting the need ...
Kazumi Yamasaki +7 more
wiley +1 more source

