Results 201 to 210 of about 22,731 (252)

Salt Treatment Confers Protection Against Acute Carp Edema Virus Reinfection While Promoting Viral Persistence

Journal of Fish Diseases, EarlyView.
ABSTRACT Carp edema virus (CEV) infects the common carp (Cyprinus carpio) and causes the lethal koi sleepy disease (KSD). Signs of KSD include respiratory, detoxification, and osmoregulatory difficulties. Salt treatment re‐equilibrates blood sodium levels and can save the fish. However, it is unclear whether these fish are immunized, remain chronically
Mikolaj Adamek, Maria Zawisza, Justin Tze Ho Chan, Alexander Rebl, Felix Teitge, Alberto Falco, Anne‐Carina Miebach, Verena Jung‐Schroers, Esteban Soto, Jiří Kyslík, Dieter Steinhagen, Krzysztof Rakus, Tomas Korytar   +12 more
wiley   +1 more source

Prevalence of Drug Resistance Associated Substitutions in Persons With Chronic Hepatitis C Infection and Virological Failure Following Initial or Re-treatment With Pan-genotypic Direct-Acting Antivirals: A Systematic Review and Meta-analysis. [PDF]

Clin Infect Dis
Inzaule S, Easterbrook P, Latona A, Ford NP, Irving W, Matthews PC, Vitoria M, Duncombe C, Giron A, McCluskey S, Lesi O, Tchamgoue S, Halford R, Adda D, Thomson E, Dusheiko G, Jordan MR.   +16 more
europepmc   +1 more source

Expanding the Fish‐Brain Invitrome With the Senegalese Sole SsB‐1 Cell Line—A Versatile Model for Neurotropic Virus Research

Journal of Fish Diseases, EarlyView.
ABSTRACT Cell lines are essential tools for studying animal physiology and immunopathology, reducing the use of live animals and supporting the 3Rs principle of reduction, refinement, and replacement. The Senegalese sole (Solea senegalensis), a relevant species for Spanish aquaculture diversification, lacks established in vitro models. We developed SsB‐
Yulema Valero, Alberto Cuesta
wiley   +1 more source

Fish Poxviruses on the Rise: Prospects for Aquatic Health

Journal of Fish Diseases, EarlyView.
ABSTRACT Fish poxviruses are increasingly recognised as emerging pathogens of fish and should be considered in cases of unexplained gill or skin pathology. Carp edema virus (CEV), the causative agent of koi sleepy disease in common carp and koi (Cyprinus carpio), represents the first known example.
Mikolaj Adamek, Marek Matras, Oluwaseun Christianah Ojelade, Motohiko Sano, Mona C. Gjessing, Tomas Korytar, Alberto Falco, Krzysztof Rakus, Verena Jung‐Schroers, Andor Doszpoly   +9 more
wiley   +1 more source

Low-Level Viremia among Adults Living with HIV on Dolutegravir-Based First-Line Antiretroviral Therapy Is a Predictor of Virological Failure in Botswana. [PDF]

Viruses
Bareng OT, Moyo S, Mudanga M, Sebina K, Koofhethile CK, Choga WT, Moraka NO, Maruapula D, Gobe I, Motswaledi MS, Musonda R, Nkomo B, Ramaabya D, Chebani T, Makuruetsa P, Makhema J, Shapiro R, Lockman S, Gaseitsiwe S.   +18 more
europepmc   +1 more source

Determinants of virological failure among HIV clients on second-line antiretroviral treatment at Felege-hiwot and University of Gondar comprehensive specialized hospitals in the Amhara Region, Northwest Ethiopia: A case-control study. [PDF]

PLoS One
Ayenew G, Agumas Y, Shibabaw T, Getaneh G, Getie M.   +4 more
europepmc   +1 more source

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Virological and immunological characteristics of HIV treatment failure

AIDS, 2000
Resistance to antiretroviral treatment is prevalent. There is limited knowledge of the determinants of disease evolution in subjects infected with multidrug-resistant HIV (MDR-HIV).Infectivity, replication, chemokine receptor usage, and env, gag, protease and reverse transcriptase sequence analysis was performed for MDR-HIV isolates from 14 HIV ...
Kaufmann D, Muñoz M, Bleiber G, Fleury S, Lotti B, Martinez R, Pichler W, Meylan P, Telenti A   +8 more
openaire   +3 more sources

Virologic Correlates of Adherence to Antiretroviral Medications and Therapeutic Failure

JAIDS Journal of Acquired Immune Deficiency Syndromes, 2002
Adherence to antiretroviral therapy affects the pharmacokinetics of antiviral drugs and activates a cascade of events ultimately leading to therapeutic success or failure. An optimal adherence usually affords minimal rounds of virus replication and rare spontaneous mutations, which are unable to be fixed in the genome because of the competition of wild-
C. F. Perno, F. Ceccherini Silberstein, A. De Luca, A. Cozzi Lepri, C. Gori, A. Cingolani, M. C. Bellocchi, M. P. Trotta, P. Piano, F. Forbici, A. Scasso, V. Vullo, A. d’Arminio Monforte, A. Antinori, for the AdICoNA Study Group   +14 more
openaire   +8 more sources