This study investigates the impact of switching to long‐acting (LA) injectable cabotegravir and rilpivirine (CAB/RPV‐LA) on immune‐activation and ‐senescence in people with HIV (PWH). Thirty‐seven PWH switching to CAB/RPV‐LA and nine continuing oral ART were analysed over 72 weeks. LA therapy led to significant reductions in activation T and senescence
Mariasilvia Guardiani +16 more
wiley +1 more source
Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi +4 more
wiley +1 more source
Prevalence and predictors of virological failure among the people living with HIV on antiretroviral treatment in East Africa: evidence from a systematic review with meta-analysis and meta-regression of published studies from 2016 to 2023. [PDF]
Namaganda MM +17 more
europepmc +1 more source
ABSTRACT The pejerrey (Odontesthes bonariensis) is a key species for recreational and commercial fisheries in Argentina and holds significant aquaculture potential. It has been introduced to various countries worldwide, including Japan, where intensive aquaculture has developed.
Aarón Torres‐Martínez +4 more
wiley +1 more source
Real-world prevalence of integrase inhibitor resistance and virological failure since adoption as guideline-preferred therapy. [PDF]
Januszka J +4 more
europepmc +1 more source
ABSTRACT In this study, we investigated the immunomodulatory effects of St. John's Wort (Hypericum perforatum) oil on the growth performance, immune responses and resistance against Lactococcus garvieae in rainbow trout (Oncorhynchus mykiss). The plant oil was incorporated into feeds at concentrations of 1, 3, and 5 g kg−1, designated as K1, K3, and K5,
Soner Bilen +3 more
wiley +1 more source
ABSTRACT Formalin‐inactivated vaccines are widely employed as a primary preventive strategy against red sea bream iridoviral disease (RSIVD), which poses a substantial economic threat to the aquaculture of rock bream (Oplegnathus fasciatus). However, conventional quantitative PCR (qPCR) cannot differentiate infectious virions from noninfectious vaccine
Sung‐Bin Moon +8 more
wiley +1 more source
Factors Affecting Virological Failure in Children Receiving First-Line Antiretroviral Therapy in Ethiopian Healthcare Facilities: A Retrospective Analysis. [PDF]
Desalegn M +4 more
europepmc +1 more source
Intraspecific Variation in the Characteristics of Cryptocaryon irritans Isolated in Japan
ABSTRACT Cryptocaryon irritans is an obligate parasitic ciliate and the causative agent of cryptocaryoniasis. This parasite is widely distributed in tropical and subtropical marine waters, and numerous outbreaks in aquaculture have been reported worldwide. Previous studies have documented variations in biological traits, such as cell size, serotype and
Hiromi Matsuoka +6 more
wiley +1 more source
Investigating rates and predictors of viral blips, low-level viraemia and virological failure in the Australian HIV observational database. [PDF]
Han WM +6 more
europepmc +1 more source

