Results 241 to 250 of about 45,169 (292)

Fatal Chronic Varicella‐Zoster Viral Infection in a Young Man With Chediak–Higashi Syndrome

Pediatric Dermatology, EarlyView.
ABSTRACT Chediak–Higashi syndrome (CHS) is a rare autosomal recessive primary immunodeficiency characterized by partial oculocutaneous albinism, neurologic involvement, and a predisposition to severe infections. Patients are particularly susceptible to developing hemophagocytic lymphohistiocytosis (HLH), which significantly worsens prognosis. We report
Albane Badet, Clément Pruvot, Zoé Manssens, Wadih Abou‐Chahla, Sébastien Buche   +4 more
wiley   +1 more source

Low-Level Viremia among Adults Living with HIV on Dolutegravir-Based First-Line Antiretroviral Therapy Is a Predictor of Virological Failure in Botswana. [PDF]

Viruses
Bareng OT, Moyo S, Mudanga M, Sebina K, Koofhethile CK, Choga WT, Moraka NO, Maruapula D, Gobe I, Motswaledi MS, Musonda R, Nkomo B, Ramaabya D, Chebani T, Makuruetsa P, Makhema J, Shapiro R, Lockman S, Gaseitsiwe S.   +18 more
europepmc   +1 more source

Determinants of virological failure among HIV clients on second-line antiretroviral treatment at Felege-hiwot and University of Gondar comprehensive specialized hospitals in the Amhara Region, Northwest Ethiopia: A case-control study. [PDF]

PLoS One
Ayenew G, Agumas Y, Shibabaw T, Getaneh G, Getie M.   +4 more
europepmc   +1 more source

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Virological and immunological characteristics of HIV treatment failure

AIDS, 2000
Resistance to antiretroviral treatment is prevalent. There is limited knowledge of the determinants of disease evolution in subjects infected with multidrug-resistant HIV (MDR-HIV).Infectivity, replication, chemokine receptor usage, and env, gag, protease and reverse transcriptase sequence analysis was performed for MDR-HIV isolates from 14 HIV ...
D, Kaufmann, M, Muñoz, G, Bleiber, S, Fleury, B, Lotti, R, Martinez, W, Pichler, P, Meylan, A, Telenti   +8 more
openaire   +2 more sources

Virologic suppression in treatment-experienced patients after virologic rebound or failure of therapy

Current Opinion in HIV and AIDS, 2011
To discuss factors related to virologic failure and review data from recent clinical trials evaluating re-suppression of viremia in extensively-treated HIV-infected patients with resistance.Factors associated with virologic failure can be related to the virus (e.g. resistance), the patient (e.g. adherence) or HIV therapy (e.g. availability) and must be
Rui, Sarmento-Castro, Carlos, Vasconcelos, Maria João, Aguas, Rui, Marques, Joaquim, Oliveira   +4 more
openaire   +2 more sources

Evaluation and management of early virological failure

Current Opinion in HIV and AIDS, 2006
To describe the causes, evaluation, and management of early virological failure in patients treated with their first antiretroviral regimen.Combination antiretroviral therapy predictably induces a rapid virological response, with the majority of patients achieving an undetectable HIV-RNA load by week 24.
openaire   +2 more sources

Virologic Outcome and Predictors of Virologic Failure of Highly Active Antiretroviral Therapy Containing Protease Inhibitors

AIDS Patient Care and STDs, 2001
In this observational single-center cohort study outside the clinical trial setting, outcome and predictors of virologic failure of highly active antiretroviral therapy (HAART) containing a protease inhibitor were evaluated in human immunodeficiency (HIV)-infected persons.
H, Knobel, A, Guelar, A, Carmona, M, Espona, A, González, J L, López-Colomés, P, Saballs, J L, Gimeno, A, Díez   +8 more
openaire   +2 more sources

Virologic Correlates of Adherence to Antiretroviral Medications and Therapeutic Failure

JAIDS Journal of Acquired Immune Deficiency Syndromes, 2002
Adherence to antiretroviral therapy affects the pharmacokinetics of antiviral drugs and activates a cascade of events ultimately leading to therapeutic success or failure. An optimal adherence usually affords minimal rounds of virus replication and rare spontaneous mutations, which are unable to be fixed in the genome because of the competition of wild-
C. F. Perno, F. Ceccherini Silberstein, A. De Luca, A. Cozzi Lepri, C. Gori, A. Cingolani, M. C. Bellocchi, M. P. Trotta, P. Piano, F. Forbici, A. Scasso, V. Vullo, A. d’Arminio Monforte, A. Antinori, for the AdICoNA Study Group   +14 more
openaire   +6 more sources