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ABSTRACT Background Human activities play a significant role in the emergence of infectious diseases. We aimed to test whether artificial irrigation affects the occurrence of a zoonotic bacteria sensitive to desiccation, pathogenic Leptospira species (pathoLep), in micromammals inhabiting Mediterranean ecosystems.
Cristina Ruiz +4 more
wiley +1 more source
Discovery of Viroids and Viroid‐Like RNAs in Plants
Plant Biotechnology Journal, EarlyView.
Zhiyou Xuan +15 more
wiley +1 more source
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Early virological failure with cabotegravir/rilpivirine.
Journal of Antimicrobial ChemotherapyL. Bailón +9 more
semanticscholar +5 more sources
Virological and immunological characteristics of HIV treatment failure
AIDS, 2000Resistance to antiretroviral treatment is prevalent. There is limited knowledge of the determinants of disease evolution in subjects infected with multidrug-resistant HIV (MDR-HIV).Infectivity, replication, chemokine receptor usage, and env, gag, protease and reverse transcriptase sequence analysis was performed for MDR-HIV isolates from 14 HIV ...
D, Kaufmann +8 more
openaire +2 more sources
Current Opinion in HIV and AIDS, 2011
To discuss factors related to virologic failure and review data from recent clinical trials evaluating re-suppression of viremia in extensively-treated HIV-infected patients with resistance.Factors associated with virologic failure can be related to the virus (e.g. resistance), the patient (e.g. adherence) or HIV therapy (e.g. availability) and must be
Rui, Sarmento-Castro +4 more
openaire +2 more sources
To discuss factors related to virologic failure and review data from recent clinical trials evaluating re-suppression of viremia in extensively-treated HIV-infected patients with resistance.Factors associated with virologic failure can be related to the virus (e.g. resistance), the patient (e.g. adherence) or HIV therapy (e.g. availability) and must be
Rui, Sarmento-Castro +4 more
openaire +2 more sources
Evaluation and management of early virological failure
Current Opinion in HIV and AIDS, 2006To describe the causes, evaluation, and management of early virological failure in patients treated with their first antiretroviral regimen.Combination antiretroviral therapy predictably induces a rapid virological response, with the majority of patients achieving an undetectable HIV-RNA load by week 24.
openaire +2 more sources
AIDS Patient Care and STDs, 2001
In this observational single-center cohort study outside the clinical trial setting, outcome and predictors of virologic failure of highly active antiretroviral therapy (HAART) containing a protease inhibitor were evaluated in human immunodeficiency (HIV)-infected persons.
H, Knobel +8 more
openaire +2 more sources
In this observational single-center cohort study outside the clinical trial setting, outcome and predictors of virologic failure of highly active antiretroviral therapy (HAART) containing a protease inhibitor were evaluated in human immunodeficiency (HIV)-infected persons.
H, Knobel +8 more
openaire +2 more sources
Virologic Correlates of Adherence to Antiretroviral Medications and Therapeutic Failure
JAIDS Journal of Acquired Immune Deficiency Syndromes, 2002Adherence to antiretroviral therapy affects the pharmacokinetics of antiviral drugs and activates a cascade of events ultimately leading to therapeutic success or failure. An optimal adherence usually affords minimal rounds of virus replication and rare spontaneous mutations, which are unable to be fixed in the genome because of the competition of wild-
C. F. Perno +14 more
openaire +6 more sources

