Results 11 to 20 of about 23,473 (201)

Perceived disabling physical pain and suicidal ideation in aging people living with HIV cured of hepatitis C: A multi-center survey in France (ANRS CO13 HEPAVIH). [PDF]

HIV Med
Abstract Introduction Suicidal ideation (SI) is highly prevalent among people living with HIV (PWH) and those with chronic hepatitis C virus (HCV) infection. Individuals with long‐term HIV–HCV co‐infection face specific health challenges, including heightened physical pain.
Barré T, Ramier C, Protopopescu C, Sogni P, Ory K, Saidi T, Abgrall S, Brégigeon-Ronot S, Carrieri P, Marcellin F, ANRS CO13 HEPAVIH Study Group.   +10 more
europepmc   +2 more sources

Prolonged Zika Virus NS1 Protein Circulation in Patient Sera Impacts Clinical Outcome Before the Rise of a Specific IgM Response. [PDF]

J Med Virol
ABSTRACT Zika virus (ZIKV) is a neurotropic virus that can be transmitted congenitally. In ZIKV‐infected pregnant women, placental dysfunction is associated with the secretion of nonstructural protein 1 (NS1). In this study, the kinetics of NS1 secretion and antibody response were assessed and characterized in the serum of ZIKV‐positive adult patients ...
Tamietti C, Stephen T, Rouvinski A, Tenebray B, Leparc-Goffard I, de Laval F, Fernandes-Pellerin S, Manuguerra JC, Rey F, Hasan M, Badaut C, Flamand M, Matheus S, Briolant S.   +13 more
europepmc   +2 more sources

Longitudinal Monitoring of Systemic Cytokines After Mild Zika Virus Infection Revealed an Association Between Th17 Polarization and Clinical and Serological Outcomes. [PDF]

J Med Virol
ABSTRACT Zika virus (ZIKV) is a neurotropic virus that can cause a variety of neurological manifestations, ranging from mild forms to severe disorders like Guillain–Barré syndrome and congenital Zika syndrome. The pathophysiology of these complications is not fully understood, but they have been linked to host immune responses, particularly a ...
Marquine S, Mura M, de Laval F, Grard G, Badaut C, Briolant S, Trignol A.   +6 more
europepmc   +2 more sources

Assessing scoring metrics for AlphaFold2 and AlphaFold3 protein complex predictions. [PDF]

Protein Sci
Abstract Recent breakthroughs in AI‐driven protein structure prediction have revolutionized structural biology, unlocking new possibilities to model complex biomolecular interactions. We evaluated widely used scoring metrics for assessing models predicted by ColabFold with templates, ColabFold without templates, and AlphaFold3.
Genz LR, Nair S, Nagar N, Topf M.
europepmc   +2 more sources

Respiratory syncytial virus in pediatric patients with severe acute respiratory infections in Senegal: findings from the 2022 sentinel surveillance season

Scientific Reports, 2023
In 2022, many regions around the world experienced a severe respiratory syncytial virus (RSV) epidemic with an earlier-than-usual start and increased numbers of paediatric patients in emergency departments.
Mamadou Malado Jallow, Moussa Moise Diagne, Samba Niang Sagne, Fatime Tall, Jean Baptisse Niokhor Diouf, Djibril Boiro, Marie Pedapa Mendy, Ndiendé Koba Ndiaye, Davy Kiori, Sara Sy, Déborah Goudiaby, Cheikh Loucoubar, Gamou Fall, Mamadou Aliou Barry, Ndongo Dia   +14 more
doaj   +1 more source

La peste des petits ruminants au Sénégal. Données nouvelles

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1976
Les auteurs rapportent l'apparition d'une importante épizootie de peste des petits ruminants au Sénégal lors de la saison des pluies 1974. Depuis cette date, la maladie provoque des pertes considérables dans différentes régions du pays.
P. Bourdin, M.P. Doutre
doaj   +1 more source

Viruses and Endocrine Diseases

Microorganisms, 2023
Viral infections have been frequently associated with physiological and pathological changes in the endocrine system for many years. The numerous early and late endocrine complications reported during the current pandemic of coronavirus disease 2019 ...
Magloire Pandoua Nekoua, Cyril Debuysschere, Inès Vergez, Corentin Morvan, Chaldam Jespere Mbani, Famara Sane, Enagnon Kazali Alidjinou, Didier Hober   +7 more
doaj   +1 more source

1-Benzyl-3-cetyl-2-methylimidazolium Iodide (NH125) Is a Broad-Spectrum Inhibitor of Virus Entry with Lysosomotropic Features

Viruses, 2018
Cellular kinases are crucial for the transcription/replication of many negative-strand RNA viruses and might serve as targets for antiviral therapy. In this study, a library comprising 80 kinase inhibitors was screened for antiviral activity against ...
Sarah Moeschler, Samira Locher, Gert Zimmer   +2 more
doaj   +1 more source

Omicron Impacts Olfaction in Hamsters. [PDF]

FASEB J
Compared to the original SARS‐CoV‐2 strain (D614G), infection by Omicron: still decreases olfactory performance in hamster; infects the olfactory epithelium with a delay and to a lesser extent; induces a strong inflammation with a delay; induces much less olfactory epithelium damage; still provokes release of cellular debris in the lumen of the nasal ...
Guérin V, Khan M, Bourgon C, Boujedli Y, Jacquelin J, von Bartheld CS, Martin-Latil S, Klonjkowski B, Le Poder S, Meunier N.   +9 more
europepmc   +2 more sources

Quantification of Enterovirus RNA in Sludge Samples Using Single Tube Real-Time RT-PCR

BioTechniques, 2000
We have developed a quantitative RTPCR method that can be used to determine the amount of enterovirus RNA in urban sludge samples. This method combines Taq-Man® technology with the ABI PrismTM 7700 real-time sequence detection system.
S. Monpoeho, A. Dehée, B. Mignotte, L. Schwartzbrod, V. Marechal, J.-C. Nicolas, S. Billaudel, V. Férré   +7 more
doaj   +1 more source