Results 101 to 110 of about 497,332 (389)

Parametric Resonance May Explain Virologic Failure to HIV Treatment Interruptions [PDF]

arXiv, 2005
Pilot studies of structured treatment interruptions (STI) in HIV therapy have shown that patients can maintain low viral loads whilst benefiting from reduced treatment toxicity. However, a recent STI clinical trial reported a high degree of virologic failure.
arxiv  

Gender Parity Trends for Invited Speakers at Four Prominent Virology Conference Series

Journal of Virology, 2017
Scientific conferences are most beneficial to participants when they showcase significant new experimental developments, accurately summarize the current state of the field, and provide strong opportunities for collaborative networking. A top-notch slate
R. Kalejta, A. Palmenberg
semanticscholar   +1 more source

Host Plasma Microenvironment in Immunometabolically Impaired HIV Infection Leads to Dysregulated Monocyte Function and Synaptic Transmission Ex Vivo

Advanced Science, EarlyView.
Network‐based risk stratification of people living with HIV (PWH) on prolonged therapy using multi‐omics data identifies 44% of the patients are at risk of immunometabolic complications. A senescence‐associated myeloid cell‐driven plasma microenvironment drives immunometabolic dysregulation in at‐risk PWH.
Flora Mikaeloff, Marco Gelpi, Alejandra Escós, Tianqi Wang, Soham Gupta, Anna Olofsson, Sara Svensson Akusjärvi, Sabrina Schuster, Prajakta Naval, Vikas Sood, Negin Nikouyan, Andreas D. Knudsen, Beate Vestad, Julie Høgh, Johannes R. Hov, Thomas Benfield, Marius Trøseid, Vinay Pawar, Marijana Rucevic, Rui Benfeitas, Ákos Végvári, Liam O'Mahony, Rajkumar Savai, Niklas K. Björkström, Magda Lourda, João Pedro de Magalhães, Siegfried Weiss, Adil Mardinoglu, Mukesh Kumar Varshney, Annika C. Karlsson, Yasir Ahmed Syed, Susanne D. Nielsen, Ujjwal Neogi   +32 more
wiley   +1 more source

Diagnostic Virology [PDF]

Clinical Infectious Diseases, 2000
Diagnostic virology has now entered the mainstream of medical practice. Multiple methods are used for the laboratory diagnosis of viral infections, including viral culture, antigen detection, nucleic acid detection, and serology. The role of culture is diminishing as new immunologic and molecular tests are developed that provide more rapid results and ...
openaire   +2 more sources

IL‐33‐Induced TREM2+ Macrophages Promote Pathological New Bone Formation Through CREG1‐IGF2R Axis in Ankylosing Spondylitis

Advanced Science, EarlyView.
This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao, Siwen Chen, Hua Chao, Zihao Li, Hao Yang, Dongying Chen, Sifang Li, Shuai Zhang, Jingyu Zhang, Jianru Wang, Zemin Li, Xiang Li, Zhongping Zhan, Tangming Guan, Yiwen Zhang, Wende Li, Hui Liu   +16 more
wiley   +1 more source

Candida species detection in patients with chronic periodontitis: A systematic review and meta‐analysis

Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1354-1375, December 2022., 2022
Abstract Objectives To assess the Candida species occurrence rate and concentration in periodontal pockets in chronic periodontitis (CP) by meta‐analysis. Materials and Methods A search was performed of articles published between January 1, 2010, and October 1, 2020, in English and in Russian, in the electronic databases MEDLINE‐PubMed, Google Scholar,
Ekaterina Slazhneva, Ekaterina Tikhomirova, Victor Tsarev, Liudmila Orekhova, Ekaterina Loboda, Victoria Atrushkevich   +5 more
wiley   +1 more source

Zika Virus Outside Africa

Emerging Infectious Diseases, 2009
Zika virus (ZIKV) is a flavivirus related to yellow fever, dengue, West Nile, and Japanese encephalitis viruses. In 2007 ZIKV caused an outbreak of relatively mild disease characterized by rash, arthralgia, and conjunctivitis on Yap Island in the ...
Edward B. Hayes
doaj   +1 more source

Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease

Advanced Science, EarlyView.
The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su, Guoqing Wu, Muya Xiong, Yuhang Wang, Junyuan Cao, Mengyuan You, Yingchun Xiang, Tianqing Nie, Minjun Li, Gengfu Xiao, Leike Zhang, Qiang Shao, Yechun Xu   +12 more
wiley   +1 more source

Implementing microwell slides for detection and isolation of single circulating tumor cells from complex cell suspensions

Cytometry Part A, Volume 101, Issue 12, Page 1057-1067, December 2022., 2022
Abstract Cell loss during detection and isolation of circulating tumor cells (CTCs) is a challenge especially when label‐free pre‐enrichment technologies are used without the aid of magnetic particles. Although microfluidic systems can remove the majority of “contaminating” white blood cells (WBCs), their remaining numbers are still impeding single CTC
Liwen Yang, Mahdi Rivandi, André Franken, Maarten Hieltjes, Pieter Jan van der Zaag, Constantin Nelep, Jens Eberhardt, Stefan Peter, Dieter Niederacher, Tanja Fehm, Hans Neubauer   +10 more
wiley   +1 more source

Development survey of neurovirology

Chinese Journal of Contemporary Neurology and Neurosurgery, 2014
As a new subdiscipline, neurovirology derives from medical virology and neurology. Its research field includes both clinical practice of viral infectious diseases of the nervous system and fundamental research of medical virology.
De-xin WANG
doaj