Results 111 to 120 of about 332,784 (298)
Regenerative perfusion bioreactor for biologics production with lower COGs
Biotechnology Progress, EarlyView.Abstract Perfusion bioreactor systems enable intensified bioprocessing with high cell densities and volumetric productivities in monoclonal antibody (mAb) manufacturing. However, their widespread adoption remains constrained by the high consumption of chemically defined cell culture media.
Eric Wynne +5 more
wiley +1 more source
Medical and molecular virology [PDF]
, 2020 Includes bibliographical references.This book was created for upper division microbiology students studying virology. It will describe the molecular biology and major diseases of virus families that cause significant disease in animals and humans.
Suchman, Erica, author
core
Lipid droplet profiling during neutrophil differentiation by stimulated Raman scattering microscopy
Biotechnology Progress, EarlyView.Abstract Lipid droplets (LDs) are dynamic organelles that serve as metabolic hubs and emerging regulators of immune cell fate. Although LDs have been implicated in immune regulation, how LD metabolism is remodeled during neutrophil differentiation and how stage‐specific LD dynamics shape mature neutrophil function remain poorly defined.
Ting‐Jung Sung +5 more
wiley +1 more source
, 2014 Plant virology in AfricaProfessor Roger Hull, of Norwich, England, writes in support of the Viewpoint article by Dr M Tresh published in Spore 76 entitled The future of plant virology in Africa. 'I strongly support the need for the enhancement of..
Technical Centre for Agricultural and Rural Cooperation
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Bone marrow‐like viscosity affects imatinib resistance in chronic myeloid leukemia
Biotechnology Progress, EarlyView.Physical cues such as microenvironmental viscosity have been recognized as important regulators in controlling cell functions. However, even though the bone marrow (BM) is a viscous tissue in which cells respond mechanically to both the matrix stiffness and the viscosity of surrounding fluid, the impact of microenvironmental viscosity on imatinib (IM ...
Tianjiao Zeng +6 more
wiley +1 more source
Biotechnology Progress, EarlyView.Abstract Recombinant adeno‐associated virus production for gene therapy applications commonly relies on the Spodoptera frugiperda 9 (Sf9) baculovirus infection platform. The process encompasses cell expansion from flasks through intermediate‐scale bioreactors to large‐scale production.
Min Tae Park, Seyed Pouria Motevalian
wiley +1 more source
BMT211 I BMT306- Virologi (Virology) [PDF]
First Semester Examination 2023/2024 Academic Session February 2024 BMT211 I BMT306- Virologi (Virology) Duration: 2 hours (Masa: 2 ...
PPSKJ, Pusat Pengajian Sains Kajihayat
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Biotechnology Progress, EarlyView.Abstract Haptoglobin (Hp) is a polymorphic acute phase α‐2 glycoprotein found in plasma that plays a critical role in binding, neutralizing, and removing cell‐free hemoglobin (Hb) from the circulation. Under clinical conditions characterized by high levels of hemolysis, such as in patients with sickle cell disease (SCD), large quantities of cell‐free ...
Shuwei Lu +5 more
wiley +1 more source
Biotechnology Progress, EarlyView.Abstract Regeneron's bispecific technology, based on a fully human IgG antibody construct, consists of two distinct heavy chains and a common light chain co‐expressed in a single cell. The co‐expression of the two distinct heavy chains, one of which contains a dipeptide substitution that ablates Protein A binding, leads to the formation of three ...
Samantha Wadsworth +4 more
wiley +1 more source
Biotechnology Progress, EarlyView.Abstract Increasing protein therapeutics production by adopting intensified perfusion cultures places high demand on the mass transfer capabilities of single‐use bioreactors (SUB). Here, we compare these capabilities for four SUB designs against worst‐case O2 transfer requirements for supporting Chinese hamster ovary (CHO) perfusion cultures. Impact of
Anita B. Dabek +9 more
wiley +1 more source