Results 101 to 110 of about 332,784 (298)

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

open access: yesBiotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson   +7 more
wiley   +1 more source

The unequivocal preponderance of biocomputation in clinical virology

open access: yes, 2018
Biocomputation in clinical virology.
Diby Paul   +6 more
core   +1 more source

Demonstration of nanofiltration‐based virus safety for AAV manufacturing using model viruses

open access: yesBiotechnology Progress, EarlyView.
Abstract Virus safety for biopharmaceutical products has been a well‐established concern for several decades. While various virus reduction steps have been identified and implemented for traditional plasma‐derived and monoclonal antibody products, there are various challenges to achieving the same virus safety in emerging gene therapy products.
Brian Buesing   +2 more
wiley   +1 more source

The 23rd Annual Meeting of the Rocky Mountain Virology Association

open access: yes
Located 50 miles west of Fort Collins, Colorado, Colorado State University’s Mountain Campus in Pingree Park hosted the 23rd annual Rocky Mountain Virology Association meeting in 2023 with 116 participants.
Ali L. Brehm   +8 more
core   +1 more source

High‐throughput development and scale‐up of recombinant adeno‐associated virus 5 anion‐exchange chromatography for high‐purity capsid separation

open access: yesBiotechnology Progress, EarlyView.
High‐throughput anion‐exchange chromatography process development enables scalable purification of high‐purity recombinant adeno‐associated virus capsids. Abstract Recombinant adeno‐associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids ...
Kevin Vera   +8 more
wiley   +1 more source

Molecular virology.:Reseña blbliográfica

open access: yes, 1985
Es reseña de: Molecular virology. Y. Becker. Martinus Nijhoff. The Hague. 1983.
Gacto Fernández, Mariano José   +1 more
core  

Virology Journal -- new OA journal on BMC

open access: yes, 2004
Virology Journal is ready to debut at BioMed Central. Virology Journal is an Open Access journal emphasizing rapid communication of high quality original research in human, animal, plant, insect, bacterial and fungal viruses.
Peter Suber
core   +1 more source

DNA concentration in harvest affects retrovirus clearance capabilities of protein A chromatography

open access: yesBiotechnology Progress, EarlyView.
Abstract Protein A chromatography is a key unit operation in biopharmaceutical purification, widely used to capture monoclonal antibodies (mAbs) from harvest cell culture fluid (HCCF). In addition to its primary function, protein A chromatography is also frequently tested for its ability to remove viruses. Although protein A specifically binds mAbs and
Lukas Döring   +7 more
wiley   +1 more source

Virology

open access: yes, 2021
Although vaccines are the cornerstone of controlling epidemics and saving lives, antivirals also have a key role to play in controlling the progression of diseases by reducing viral loads and could be used to break SARS-CoV-2 community transmission chains by limiting viral shedding levels and duration.
openaire   +1 more source

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