Results 101 to 110 of about 332,784 (298)
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson +7 more
wiley +1 more source
The unequivocal preponderance of biocomputation in clinical virology
Biocomputation in clinical virology.
Diby Paul +6 more
core +1 more source
Demonstration of nanofiltration‐based virus safety for AAV manufacturing using model viruses
Abstract Virus safety for biopharmaceutical products has been a well‐established concern for several decades. While various virus reduction steps have been identified and implemented for traditional plasma‐derived and monoclonal antibody products, there are various challenges to achieving the same virus safety in emerging gene therapy products.
Brian Buesing +2 more
wiley +1 more source
The 23rd Annual Meeting of the Rocky Mountain Virology Association
Located 50 miles west of Fort Collins, Colorado, Colorado State University’s Mountain Campus in Pingree Park hosted the 23rd annual Rocky Mountain Virology Association meeting in 2023 with 116 participants.
Ali L. Brehm +8 more
core +1 more source
High‐throughput anion‐exchange chromatography process development enables scalable purification of high‐purity recombinant adeno‐associated virus capsids. Abstract Recombinant adeno‐associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids ...
Kevin Vera +8 more
wiley +1 more source
Molecular virology.:Reseña blbliográfica
Es reseña de: Molecular virology. Y. Becker. Martinus Nijhoff. The Hague. 1983.
Gacto Fernández, Mariano José +1 more
core
Virology Journal -- new OA journal on BMC
Virology Journal is ready to debut at BioMed Central. Virology Journal is an Open Access journal emphasizing rapid communication of high quality original research in human, animal, plant, insect, bacterial and fungal viruses.
Peter Suber
core +1 more source
DNA concentration in harvest affects retrovirus clearance capabilities of protein A chromatography
Abstract Protein A chromatography is a key unit operation in biopharmaceutical purification, widely used to capture monoclonal antibodies (mAbs) from harvest cell culture fluid (HCCF). In addition to its primary function, protein A chromatography is also frequently tested for its ability to remove viruses. Although protein A specifically binds mAbs and
Lukas Döring +7 more
wiley +1 more source
Although vaccines are the cornerstone of controlling epidemics and saving lives, antivirals also have a key role to play in controlling the progression of diseases by reducing viral loads and could be used to break SARS-CoV-2 community transmission chains by limiting viral shedding levels and duration.
openaire +1 more source

