Results 131 to 140 of about 271,429 (263)

Mechanistic deconvolution of BSA size variants by constrained Raman pseudo‐Voigt hard modeling during anion‐exchange chromatography

Biotechnology Progress, EarlyView.
Abstract In biopharmaceutical manufacturing, protein aggregation is a critical quality attribute, necessitating rapid and reliable analytical strategies during downstream processes like anion‐exchange chromatography (AEX). While Raman spectroscopy enables continuous monitoring of protein secondary structure, standard data‐driven regression models ...
Jakob Heyer‐Müller, Robin Schiemer, Lars Robbel, Michael Schmitt, Jürgen Hubbuch   +4 more
wiley   +1 more source

Editorial: Virology today in Spain. Selected topics from Spanish virology

Frontiers in Cellular and Infection Microbiology
Covadonga Alonso, Josep Quer, Josep Quer, Josep Quer, Isabel García-Dorival   +4 more
doaj   +1 more source

Genome sequence of a mumps virus isolated from the cerebrospinal fluid of a Vietnamese child with meningitis. [PDF]

Microbiol Resour Announc
Tran XD, Dao TL, To MM, La Scola B, Colson P, Gautret P.   +5 more
europepmc   +1 more source

Scalable catalyst production process for oleate hydratase whole‐cell biocatalysis

Biotechnology Progress, EarlyView.
This study establishes a scalable lactose‐induced fed‐batch fermentation for an Escherichia coli whole‐cell biocatalyst containing an oleate hydratase. Operation at a higher growth rate markedly increased biomass yields while maintaining catalyst activity and was demonstrated at 150 L scale.
Rebekka Horstmann, Mario Beckers, Jörn Viell, Fabian Allan Watt, Valentin Steier, Marcel Mann, Jørgen B. Magnus   +6 more
wiley   +1 more source

Genome sequence of seven human herpes simplex virus 2 (HSV2) clinical isolates from Finland. [PDF]

Microbiol Resour Announc
Bowen CD, Renner DW, Paavilainen H, Vuorinen T, Hukkanen V, Szpara ML.   +5 more
europepmc   +1 more source

The Problems of Virology

American Journal of Public Health and the Nations Health, 1951
openaire   +3 more sources

Application of commercial ultrafiltration membranes for protein purification by high performance countercurrent membrane purification (HPCMP)

Biotechnology Progress, EarlyView.
Abstract High performance countercurrent membrane purification (HPCMP) has emerged as a promising diffusive separation strategy for the purification of recombinant proteins and monoclonal antibodies (mAbs). However, prior studies employed dialysis membranes, which are designed for diffusive separations but have not been validated for biopharmaceutical ...
Aylin Mohammadzadehmarandi, Nate Heller, Mohammadreza Ahmadimashhadi, Jon Petrone, Nicholas Marchand, Siavash Darvishmanesh, Ka Zhang, Stefano Menegatti, Andrew L. Zydney   +8 more
wiley   +1 more source

Corrigendum: A single amino acid in coat protein of Pepper mild mottle virus determines its subcellular localization and the chlorosis symptom on leaves of pepper. [PDF]

J Gen Virol
Han K, Zheng H, Ji M, Cui W, Hu S, Peng J, Zhao J, Lu Y, Lin L, Liu Y, Chen J, Yan F.   +11 more
europepmc   +1 more source

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

Biotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson, Jessica Willmott, Holly Corrigall, Daniela Lega, Joseph Stirling, Vithiya Vimalraj, Mitul Patel, Robyn Emmins   +7 more
wiley   +1 more source

Biographical Feature: Benjamin A. Pinsky, MD, PhD. [PDF]

J Clin Microbiol
Munson E.
europepmc   +1 more source