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The birth of virology [PDF]

open access: yesAntonie van Leeuwenhoek, 1997
This quote is from Cicero’s ‘De Amicitia’ (23, 87) — I happen to remember it from my days at school, and it comes in conveniently to start a talk on the birth of virology, my occupation since three decades. In Cicero’s quote it is said of an intransigent person that she ‘...still cannot be without somebody where to spit out the venom of one’s own ...
openaire   +3 more sources

A Review on SARS-CoV-2 Virology, Pathophysiology, Animal Models, and Anti-Viral Interventions

open access: yesPathogens, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of CoV disease 2019 (COVID-19) is a highly pathogenic and transmissible CoV that is presently plaguing the global human population and economy.
S. Neerukonda, Upendra K. Katneni
semanticscholar   +1 more source

Uncovering Virus-Virus Interactions by Unifying Approaches and Harnessing High-Throughput Tools

open access: yesmSystems, 2019
Virus-host interactions have received much attention in virology. Virus-virus interactions can occur when >1 virus infects a host and can be deemed social when one virus affects the fitness of another virus, as in the well-known case of superinfection ...
Samuel L. Díaz-Muñoz
doaj   +1 more source

TEMPOL inhibits SARS-CoV-2 replication and development of lung disease in the Syrian hamster model

open access: yesiScience, 2022
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide outbreak, known as coronavirus disease 2019 (COVID-19). Alongside vaccines, antiviral therapeutics is an important part of the healthcare response to COVID-19 ...
Nunziata Maio   +5 more
doaj   +1 more source

Comparison of Intracellular Transcriptional Response of NHBE Cells to Infection with SARS-CoV-2 Washington and New York Strains

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China in December 2019 and caused a global pandemic resulting in millions of deaths and tens of millions of patients positive tests.
Tiana M. Scott   +6 more
doaj   +1 more source

Physical virology: From virus self‐assembly to particle mechanics

open access: yesWiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2020
Viruses are highly ordered supramolecular complexes that have evolved to propagate by hijacking the host cell's machinery. Although viruses are very diverse, spreading through cells of all kingdoms of life, they share common functions and properties ...
P. Buzón, S. Maity, W. Roos
semanticscholar   +1 more source

Evaluation of ELISA-Based Multiplex Peptides for the Detection of Human Serum Antibodies Induced by Zika Virus Infection across Various Countries

open access: yesViruses, 2021
Zika virus (ZIKV) is a mosquito-borne Flavivirus with a positive-sense RNA genome, which are generally transmitted through the bite of an infected Aedes mosquito. ZIKV infections could be associated with neurological sequelae that, and otherwise produces
Maria del Pilar Martinez Viedma   +22 more
doaj   +1 more source

Cell Cultures for Virology: Usability, Advantages, and Prospects

open access: yesInternational Journal of Molecular Sciences, 2020
Virus detection in natural and clinical samples is a complicated problem in research and diagnostics. There are different approaches for virus isolation and identification, including PCR, CRISPR/Cas technology, NGS, immunoassays, and cell-based assays ...
A. A. Dolskiy, I. Grishchenko, D. Yudkin
semanticscholar   +1 more source

Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile

open access: yesiScience, 2021
Summary: Broadly neutralizing antibodies (bnAbs) against HIV-1 are frequently associated with the presence of autoreactivity/polyreactivity, a property that can limit their use as therapeutic agents.
Edurne Rujas   +16 more
doaj   +1 more source

Virus goes viral: an educational kit for virology classes

open access: yesVirology Journal, 2020
Viruses are the most numerous entities on Earth and have also been central to many episodes in the history of humankind. As the study of viruses progresses further and further, there are several limitations in transferring this knowledge to undergraduate
Gabriel Augusto Pires de Souza   +5 more
semanticscholar   +1 more source

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