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This quote is from Cicero’s ‘De Amicitia’ (23, 87) — I happen to remember it from my days at school, and it comes in conveniently to start a talk on the birth of virology, my occupation since three decades. In Cicero’s quote it is said of an intransigent person that she ‘...still cannot be without somebody where to spit out the venom of one’s own ...
openaire +3 more sources
A Review on SARS-CoV-2 Virology, Pathophysiology, Animal Models, and Anti-Viral Interventions
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of CoV disease 2019 (COVID-19) is a highly pathogenic and transmissible CoV that is presently plaguing the global human population and economy.
S. Neerukonda, Upendra K. Katneni
semanticscholar +1 more source
Uncovering Virus-Virus Interactions by Unifying Approaches and Harnessing High-Throughput Tools
Virus-host interactions have received much attention in virology. Virus-virus interactions can occur when >1 virus infects a host and can be deemed social when one virus affects the fitness of another virus, as in the well-known case of superinfection ...
Samuel L. Díaz-Muñoz
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TEMPOL inhibits SARS-CoV-2 replication and development of lung disease in the Syrian hamster model
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide outbreak, known as coronavirus disease 2019 (COVID-19). Alongside vaccines, antiviral therapeutics is an important part of the healthcare response to COVID-19 ...
Nunziata Maio+5 more
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China in December 2019 and caused a global pandemic resulting in millions of deaths and tens of millions of patients positive tests.
Tiana M. Scott+6 more
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Physical virology: From virus self‐assembly to particle mechanics
Viruses are highly ordered supramolecular complexes that have evolved to propagate by hijacking the host cell's machinery. Although viruses are very diverse, spreading through cells of all kingdoms of life, they share common functions and properties ...
P. Buzón, S. Maity, W. Roos
semanticscholar +1 more source
Zika virus (ZIKV) is a mosquito-borne Flavivirus with a positive-sense RNA genome, which are generally transmitted through the bite of an infected Aedes mosquito. ZIKV infections could be associated with neurological sequelae that, and otherwise produces
Maria del Pilar Martinez Viedma+22 more
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Cell Cultures for Virology: Usability, Advantages, and Prospects
Virus detection in natural and clinical samples is a complicated problem in research and diagnostics. There are different approaches for virus isolation and identification, including PCR, CRISPR/Cas technology, NGS, immunoassays, and cell-based assays ...
A. A. Dolskiy, I. Grishchenko, D. Yudkin
semanticscholar +1 more source
Summary: Broadly neutralizing antibodies (bnAbs) against HIV-1 are frequently associated with the presence of autoreactivity/polyreactivity, a property that can limit their use as therapeutic agents.
Edurne Rujas+16 more
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Virus goes viral: an educational kit for virology classes
Viruses are the most numerous entities on Earth and have also been central to many episodes in the history of humankind. As the study of viruses progresses further and further, there are several limitations in transferring this knowledge to undergraduate
Gabriel Augusto Pires de Souza+5 more
semanticscholar +1 more source