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Abstract Viruses have established relationships with almost every other living organism on Earth and at all levels of biological organization: from other viruses up to entire ecosystems. In most cases, they peacefully coexist with their hosts, but in most relevant cases, they parasitize them and induce diseases and pandemics, such as the
Ricard Solé+2 more
openaire +6 more sources
Identification of a Novel Deltavirus in Boa Constrictors
Hepatitis D virus (HDV) forms the genus Deltavirus unassigned to any virus family. HDV is a satellite virus and needs hepatitis B virus (HBV) to make infectious particles.
Udo Hetzel+6 more
doaj +1 more source
SARS-CoV-2 (COVID-19) by the numbers
The COVID-19 pandemic is a harsh reminder of the fact that, whether in a single human host or a wave of infection across continents, viral dynamics is often a story about the numbers.
Yinon M Bar-On+3 more
doaj +1 more source
Dynamics of icosahedral viruses: what does Viral Tiling Theory teach us? [PDF]
We present a top-down approach to the study of the dynamics of icosahedral virus capsids, in which each protein is approximated by a point mass. Although this represents a rather crude coarse-graining, we argue that it highlights several generic features of vibrational spectra which have been overlooked so far.
arxiv +1 more source
Structural puzzles in virology solved with an overarching icosahedral design principle
Viruses have evolved protein containers with a wide spectrum of icosahedral architectures to protect their genetic material. The geometric constraints defining these container designs, and their implications for viral evolution, are open problems in ...
R. Twarock, A. Luque
semanticscholar +1 more source
The coronavirus disease 2019 (COVID-19) moment has stimulated multiple intellectual attempts to make sense of the pandemic. The complexity of the challenge obviously requires an interdisciplinary approach.
Rian Venter
doaj +1 more source
Application of Machine Learning in understanding plant virus pathogenesis: Trends and perspectives on emergence, diagnosis, host-virus interplay and management [PDF]
Inclusion of high throughput technologies in the field of biology has generated massive amounts of biological data in the recent years. Now, transforming these huge volumes of data into knowledge is the primary challenge in computational biology. The traditional methods of data analysis have failed to carry out the task.
arxiv
At the crossroads of epidemiology and biology: bridging the gap between SARS-CoV-2 viral strain properties and epidemic wave characteristics [PDF]
The COVID-19 pandemic has given rise to numerous articles from different scientific fields (epidemiology, virology, immunology, airflow physics...) without any effort to link these different insights. In this review, we aim to establish relationships between epidemiological data and the characteristics of the virus strain responsible for the epidemic ...
arxiv
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source
Evolution of Virology: Science History through Milestones and Technological Advancements
The history of virology, which is marked by transformative breakthroughs, spans microbiology, biochemistry, genetics, and molecular biology. From the development of Jenner’s smallpox vaccine in 1796 to 20th-century innovations such as ultrafiltration and
Kunlan Zuo+9 more
doaj +1 more source