ΦCrAss001 represents the most abundant bacteriophage family in the human gut and infects Bacteroides intestinalis [PDF]
peer-reviewedCrAssphages are an extensive and ubiquitous family of tailed bacteriophages, predicted to infect bacteria of the order Bacteroidales. Despite being found in ~50% of individuals and representing up to 90% of human gut viromes, members of this
Draper, Lorraine A. +6 more
core +5 more sources
Improving the reporting of metagenomic virome-scale data
Over the last decade metagenomic sequencing has facilitated an increasing number of virome-scale studies, leading to an exponential expansion in understanding of virus diversity. This is partially driven by the decreasing costs of metagenomic sequencing,
Wei-Shan Chang +7 more
semanticscholar +1 more source
Alterations in the gut virome in patients with ankylosing spondylitis
Introduction Ankylosing spondylitis (AS), a chronic autoimmune disease, has been linked to the gut bacteriome. Methods To investigate the characteristics of the gut virome in AS, we profiled the gut viral community of 193 AS patients and 59 healthy ...
Chen Li +11 more
semanticscholar +1 more source
Pan‐European Fragile Populations Cohort for COVID‐19: What Worked, What Didn't, and Lessons Learned
ABSTRACT The COVID‐19 pandemic exposed the vulnerability of immunocompromised hosts and the scarcity of evidence guiding their management. Within the European Horizon 2020 ORCHESTRA project, a multinational consortium connected existing and new cohorts to harmonize data, laboratory methods, and clinical expertise across fragile populations. The fragile
Beatrice Tazza +11 more
wiley +1 more source
Domestic cat hepadnavirus (DCH) belongs to the Hepadnaviridae family together with human hepatitis B virus (HBV) that remains to be a major health problem worldwide.
Sabrina Wahyu Wardhani +6 more
doaj +1 more source
Improved single-swab sample preparation for recovering bacterial and phage DNA from human skin and wound microbiomes. [PDF]
BackgroundCharacterization of the skin and wound microbiome is of high biomedical interest, but is hampered by the low biomass of typical samples. While sample preparation from other microbiomes (e.g., gut) has been the subject of extensive optimization,
Chen, Irene A +3 more
core +1 more source
Integrated gut virome and bacteriome dynamics in COVID-19 patients
SARS-CoV-2 is the cause of the current global pandemic of COVID-19; this virus infects multiple organs, such as the lungs and gastrointestinal tract. The microbiome in these organs, including the bacteriome and virome, responds to infection and might ...
Jiabao Cao +19 more
semanticscholar +1 more source
A blood safety perspective on emerging arboviral infections in the United Kingdom
Abstract A core focus of the blood services is to maintain the blood supply whilst simultaneously being vigilant for potential threats to blood safety. At present, West Nile virus (WNV), Usutu virus (USUV), Dengue virus (DENV) and Tick‐borne encephalitis virus (TBEV) are considered primary arboviral threats to blood safety in the UK and Northern Europe.
Piya Rajendra +5 more
wiley +1 more source
The gut virome: the ‘missing link’ between gut bacteria and host immunity?
The human gut virome includes a diverse collection of viruses that infect our own cells as well as other commensal organisms, directly impacting on our well-being. Despite its predominance, the virome remains one of the least understood components of the
Indrani Mukhopadhya +4 more
doaj +1 more source
Depth-related distribution of a key gene of the tetraether lipid biosynthetic pathway in marine Thaumarchaeota [PDF]
The distribution of isoprenoid glycerol dialkyl glycerol tetraethers (GDGT) lipids synthesized by Thaumarchaeota has been shown to be temperature-dependent in world oceans.
Schouten, S. +2 more
core +1 more source

