Results 11 to 20 of about 27,797 (299)
The Human Virome in Health and Its Remodeling During HIV Infection and Antiretroviral Therapy: A Narrative Review [PDF]
MicroorganismsThe human virome represents a fundamental yet understudied component of the microbiome, influencing immune regulation and disease. Given the profound immune dysregulation and microbial imbalance associated with HIV infection, understanding virome ...
Federico Cesanelli +7 more
doaj +2 more sources
The gut virome: A new microbiome component in health and disease
EBioMedicine, 2022 Summary: The human gastrointestinal tract harbours an abundance of viruses, collectively known as the gut virome. The gut virome is highly heterogeneous across populations and is linked to geography, ethnicity, diet, lifestyle, and urbanisation.
Zhirui Cao +5 more
doaj +2 more sources
Uncovering Earth’s virome [PDF]
Nature, 2016 Viruses are the most abundant biological entities on Earth, but challenges in detecting, isolating, and classifying unknown viruses have prevented exhaustive surveys of the global virome. Here we analysed over 5 Tb of metagenomic sequence data from 3,042 geographically diverse samples to assess the global distribution, phylogenetic diversity, and host ...
David Páez-Espino +8 more
semanticscholar +5 more sources
The Next Generation Fecal Microbiota Transplantation: To Transplant Bacteria or Virome
Advanced Science, 2023 Fecal microbiota transplantation (FMT) has emerged as a promising therapeutic approach for dysbiosis‐related diseases. However, the clinical practice of crude fecal transplants presents limitations in terms of acceptability and reproductivity ...
You Yu, Weihong Wang, Faming Zhang
doaj +2 more sources
A metagenomic catalog of the early-life human gut virome
Nature CommunicationsEarly-life human gut microbiome is a pivotal driver of gut homeostasis and infant health. However, the viral component (known as “virome”) remains mostly unexplored.
Shuqin Zeng +11 more
doaj +2 more sources
The human gut virome: composition, colonization, interactions, and impacts on human health
Frontiers in Microbiology, 2023 The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in many disease states, but it is unknown to what extent the gut virome impacts everyday human health.
Evan Pargin +9 more
doaj +2 more sources
Gut virome and its implications in the pathogenesis and therapeutics of inflammatory bowel disease
BMC MedicineInflammatory bowel disease (IBD) refers to chronic, recurrent inflammatory intestinal disorders, primarily including Crohn’s disease (CD) and Ulcerative colitis (UC). Numerous studies have elucidated the importance of the gut microbiome in IBD. Recently,
Yushan Wu +7 more
doaj +2 more sources
MicrobiomeBackground The gut virome has been implicated in inflammatory bowel disease (IBD), yet a full understanding of the gut virome in IBD patients, especially across diverse geographic populations, is lacking.
Xiangge Tian +11 more
doaj +2 more sources
Nature CommunicationsGut bacteriome dysbiosis is known to be implicated in the pathogenesis of inflammatory bowel disease (IBD). Crohn’s disease (CD) is an IBD subtype with extensive mucosal inflammation, yet the mucosal virome, an empirical modulator of the bacteriome and ...
Zhirui Cao +13 more
doaj +2 more sources
The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges [PDF]
Advanced GeneticsThe human respiratory virome is an underexplored component of the microbiome that includes diverse DNA and RNA viruses such as eukaryotic viruses, bacteriophages, and archaeal viruses.
Xiaoxuan Yao, Xiaohui Zou, Bin Cao
doaj +2 more sources