Results 61 to 70 of about 24,085 (262)
From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies
Portal Hypertension &Cirrhosis, EarlyView.This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu +5 more
wiley +1 more source
Microbiology SpectrumLittle is known about the urinary virome and how it interacts with the host, particularly in renal transplant diseases. Using metagenomic sequencing, we characterized the urinary virome of 23 kidney transplant recipients longitudinally (11 BKV+ patients ...
Rabia Maqsood +3 more
doaj +1 more source
Choice of assembly software has a critical impact on virome characterisation
Microbiome, 2019 Background The viral component of microbial communities plays a vital role in driving bacterial diversity, facilitating nutrient turnover and shaping community composition.
Thomas D. S. Sutton +4 more
doaj +1 more source
Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease
Portal Hypertension &Cirrhosis, EarlyView.MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang +5 more
wiley +1 more source
Virome Sequencing of the Human Intestinal Mucosal–Luminal Interface
Frontiers in Cellular and Infection Microbiology, 2020 While the human gut virome has been increasingly explored in recent years, nearly all studies have been limited to fecal sampling. The mucosal–luminal interface has been established as a viable sample type for profiling the microbial biogeography of the ...
Austin Yan +4 more
doaj +1 more source
Macrobiota — helminths as active participants and partners of the microbiota in host intestinal homeostasis [PDF]
, 2016 Important insights have recently been gained in our understanding of the intricate relationship in the intestinal milieu between the vertebrate host mucosal immune response, commensal bacteria, and helminths. Helminths are metazoan worms (macrobiota) and
Gause, William C., Maizels, Rick M.
core +1 more source
, 2023 By profiling 4,143 bat individuals from 40 species, we prepared a compendium of 8,176 viral metagenomes, named BtCN-Virome. It expands the known bat RNA virus diversity by at least 3.4 folds. The data set provides important insights into understanding the diversity and circulation pattern of bat viruses.
openaire +1 more source
Iflaviruses in arthropods: when small is mighty
Insect Science, EarlyView.Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia +3 more
wiley +1 more source
Metagenomic characterisation of the viral community of lough neagh, the largest freshwater lake in Ireland [PDF]
, 2016 Lough Neagh is the largest and the most economically important lake in Ireland. It is also one of the most nutrient rich amongst the world's major lakes.
Allen, Christopher C R +9 more
core +6 more sources
Virome in the Lungs: The Role of Anelloviruses in Childhood Respiratory Diseases
Microorganisms, 2021 More recently, increasing attention has been directed to exploring the function of the global virome in health and disease. Currently, by new molecular techniques, such as metagenomic DNA sequencing, the virome has been better unveiled.
Giulia Dodi +4 more
doaj +1 more source