Ecological and evolutionary dynamics of cell-virus-virophage systems. [PDF]
PLoS Computational Biology, 2023 Microbial eukaryotes, giant viruses and virophages form a unique hyperparasitic system. Virophages are parasites of the virus transcription machinery and can interfere with virus replication, resulting in a benefit to the eukaryotic host population ...
Jose Gabriel Nino Barreat +1 more
doaj +6 more sources
Sputnik virophage disrupts the transcriptional regulation of its host giant virus [PDF]
Journal of VirologySputnik virophages are small double-stranded DNA (dsDNA) viruses that replicate only inside host amoebae infected with giant dsDNA viruses, mimiviruses.
Jingjie Chen +2 more
doaj +6 more sources
Updated Virophage Taxonomy and Distinction from Polinton-like Viruses [PDF]
Biomolecules, 2023 Virophages are small dsDNA viruses that hijack the machinery of giant viruses during the co-infection of a protist (i.e., microeukaryotic) host and represent an exceptional case of “hyperparasitism” in the viral world.
Simon Roux +5 more
doaj +3 more sources
Simultaneous Giant Virus and Virophage Quantification Using Droplet Digital PCR [PDF]
Viruses, 2022 Viruses are an abundant component of aquatic systems, but their detection and quantification remain a challenge. Virophages co-replicate with giant viruses in the shared host cell, and can inhibit the production of new giant virus particles, thereby ...
Ana del Arco +2 more
doaj +3 more sources
Conserved tripartite tail proteins mediate virophage-host interactions through Synechococcus lipopolysaccharide binding [PDF]
Journal of VirologyVirophages are small double-stranded DNA viruses that parasitize giant viruses and play crucial roles in microbial ecosystem dynamics. In this study, we investigate three evolutionarily conserved tail proteins in Dishui Lake Virophage 2 (DSLV2) that ...
Ting Chu +12 more
doaj +3 more sources
The Discovery of a New Mimivirus Isolate in Association with Virophage-Transpoviron Elements in Brazil Highlights the Main Genomic and Evolutionary Features of This Tripartite System [PDF]
Viruses, 2022 Mimiviruses are giant viruses of amoeba that can be found in association with virophages. These satellite-like viruses are dependent on the mimivirus viral factory to replicate.
Bruna Luiza de Azevedo +4 more
doaj +3 more sources
Virophages and retrotransposons colonize the genomes of a heterotrophic flagellate [PDF]
eLife, 2021 Virophages can parasitize giant DNA viruses and may provide adaptive anti-giant virus defense in unicellular eukaryotes. Under laboratory conditions, the virophage mavirus integrates into the nuclear genome of the marine flagellate Cafeteria burkhardae ...
Thomas Hackl +4 more
doaj +5 more sources
A billion years arms-race between viruses, virophages, and eukaryotes [PDF]
eLife, 2023 Bamfordviruses are arguably the most diverse group of viruses infecting eukaryotes. They include the Nucleocytoplasmic Large DNA viruses (NCLDVs), virophages, adenoviruses, Mavericks and Polinton-like viruses.
Jose Gabriel Nino Barreat +1 more
doaj +5 more sources
Seasonal dynamics and diversity of Antarctic marine viruses reveal a novel viral seascape [PDF]
Nature CommunicationsThe Southern Ocean microbial ecosystem, with its pronounced seasonal shifts, is vulnerable to the impacts of climate change. Since viruses are key modulators of microbial abundance, diversity, and evolution, we need a better understanding of the effects ...
Gonçalo J. Piedade +11 more
doaj +6 more sources
Diversity, Relationship, and Distribution of Virophages and Large Algal Viruses in Global Ocean Viromes [PDF]
Viruses, 2023 Virophages are a group of small double-stranded DNA viruses that replicate and proliferate with the help of the viral factory of large host viruses. They are widely distributed in aquatic environments but are more abundant in freshwater ecosystems. Here,
Zhenqi Wu +4 more
doaj +2 more sources