Results 151 to 160 of about 18,764 (290)
The impact of hypoxia on oncolytic virotherapy [PDF]
, 2011 The hypoxic tumor microenvironment plays significant roles in tumor cell metabolism and survival, tumor growth, and progression. Hypoxia modulates target genes in target cells mainly through an oxygen-sensing signaling pathway mediated by hypoxia ...
Sheng Guo, Z
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An evaluation of the efficacy of adenovirus-mediated gene therapy with p53 for the treatment of cancer [PDF]
, 2015 Cancer is the second leading cause of mortality in the United States today, and equally prevalent throughout the world. Traditional treatments such as chemotherapy and radiotherapy have thus far proven unable to treat the disease with high efficacy, with
Liepart IV, George Hampson
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The oncolytic virus dl922-947 reduces IL-8/CXCL8 and MCP-1/CCL2 expression and impairs angiogenesis and macrophage infiltration in anaplastic thyroid carcinoma [PDF]
, 2015 Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human solid tumor and current treatments are ineffective in increasing patients' survival. Thus, the development of new therapeutic approaches for ATC is needed.
Ayyoub +71 more
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Stem Cells International, 2017 Antitumor efficacy of systemically administered oncolytic adenoviruses (OAdv) is limited due to diverse factors such as liver sequestration, neutralizing interactions in blood, elimination by the immune system, and physical barriers in tumors.
R. Moreno +6 more
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Oncolytic Viroradiotherapy for Neuroblastoma [PDF]
, 2014 College of Education and Human Ecology Undergraduate Research ScholarshipNeuroblastoma is the most common extra-cranial solid tumor in childhood and the leading cause of childhood cancer mortality.
Kunkler, Anne
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Measles: What we have learned from non-human primate models [PDF]
, 2018 Studies in non-human primates (NHPs) have been crucial for our understanding of measles as a high impact viral disease of humans. Over a century ago, inoculations of NHPs with filtered secretions from measles patients first identified a virus as the ...
Swart, R.L. (Rik) de
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Editorial: Oncolytic virotherapy
Frontiers in Molecular Biosciences, 2023 Ahmed Majeed Al-Shammari +2 more
openaire +3 more sources
Oncolytic virotherapy: new weapon for breast cancer treatment [PDF]
, 2020 Veronica Martini +5 more
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OncoImmunology, 2019 Antitumor cytotoxic T lymphocytes (CTLs) are essential for immune surveillance, yet the blockade of eliciting such CTLs during oncolytic virotherapy remains incompletely understood.
Zhiwu Tan +9 more
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Doxorubicin hydrochloride enhanced antitumour effect of CEA‐regulated oncolytic virotherapy in live cancer cells and a mouse model [PDF]
, 2020 Boduan Xiao +11 more
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