Results 221 to 230 of about 3,791,486 (287)

Population Pharmacokinetic and Pharmacodynamic Prediction for Tebipenem Pivoxil Treatment of Pediatric Shigellosis. [PDF]

Clin Transl Sci
Zhang CX, Nuzhat S, Islam MR, Bashar SJ, Das S, Amin R, Qadri F, Khanam F, Ahmed D, Pavlinac PB, Chisti MJ, Ahmed T, Arnold SLM.   +12 more
europepmc   +1 more source

TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux

Advanced Science, EarlyView.
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang, Lijuan Wang, Dianwen Han, Peng Su, Bing Chen, Wenjing Zhao, Tong Chen, Ning Zhang, Xiaolong Wang, Yiran Liang, Yaming Li, Chen Li, Xi Chen, Dan Luo, Qifeng Yang   +14 more
wiley   +1 more source

Benefits and outcomes of implementing virtual health clinics in remote and underserved areas: a scoping review. [PDF]

Int J Technol Assess Health Care
Poudineh Moghadam M, Bazi A, Esfahani P, Emadi V.   +3 more
europepmc   +1 more source

Diffusion‐MRI‐Based Estimation of Cortical Architecture via Machine Learning (DECAM) in Primate Brains

Advanced Science, EarlyView.
We present Diffusion‐MRI‐based Estimation of Cortical Architecture via Machine Learning (DECAM), a deep‐learning framework for estimating primate brain cortical architecture optimized with best response constraint and cortical label vectors. Trained using macaque brain high‐resolution multi‐shell dMRI and histology data, DECAM generates high‐fidelity ...
Tianjia Zhu, Minhui Ouyang, Shufang Tan, Jianlin Guo, Ziqin Zhang, Xuan Liu, Risheng Liu, Hao Huang   +7 more
wiley   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Assessing Patient Acceptance of Being Offered a Virtual Calm Room in Psychiatric Inpatient Care: Mixed Methods Study. [PDF]

JMIR Form Res
Ilioudi M, Steingrimsson S, Wallström S, Osmanovic Thunström A, Lindner P, Ioannou M, Falk Ö, Ali L.   +7 more
europepmc   +1 more source

Integrating Immersive Virtual Reality Meditation into Palliative Oncology: A Randomized Trial Protocol for Evaluating Pain Relief and Quality of Life. [PDF]

Healthcare (Basel)
Montarroyos ES, Lima S, Barreto R, Moysés R, Cardenas LZ.   +4 more
europepmc   +1 more source

"Your Digital Doctor Will Now See You": A Narrative Review of VR and AI Technology in Chronic Illness Management. [PDF]

Healthcare (Basel)
Łukasik A, Celebudzka M, Gut A.
europepmc   +1 more source