Results 81 to 90 of about 1,093,531 (288)

A Dynamic Gate Enables Regioselective Hydroxylation of Free Arginine by a Non‐Canonical Heme Enzyme

Advanced Science, EarlyView.
The YqcI/YcgG enzyme AglA employs a unique “sandwich” fold and a dynamic gating mechanism to selectively hydroxylate AMPn‐Arg at Nε. Site‐directed mutations reprogram regioselectivity or enable activity on free arginine by altering hydrogen‐bond networks, precisely positioning substrates.
Yuan Sun, Chao Dou, Weizhu Yan, Pengpeng Chen, Lu Zhang, Dan Zhou, Yanhui Zheng, Zhaolin Long, Shoujie Li, Xiaoqing Xu, Qiuxia Huang, Xiaofeng Zhu, Wei Cheng   +12 more
wiley   +1 more source

Wissenschaftliche Konferenzen in Social Virtual Reality

E-learning and Education, 2022
In November/December 2020, one of the first scientific conferences per Social Virtual Reality (SocialVR) was held. The conference, which lasted several weeks, addressed the anchoring of virtual and augmented reality (VR/AR) technologies in vocational ...
Raphael Zender, Miriam Mulders
doaj  

Preface of the Book of Proceedings of the Virtual Conference on Chemistry and its Applications (VCCA-2021) [PDF]

, 2022

openalex   +1 more source

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

The Virtual Conference: Extending Professional Education in Cyberspace [PDF]

, 1996
This paper describes the use of Internet based tools to support professional interaction and education in a format known as the virtual conference. The paper discusses characteristics of the virtual conference and presents data from a case study in ...
Anderson, Terry
core   +1 more source

PacMap: Transferring PacMan to the Physical Realm

, 2015
This paper discusses the implementation of the pervasive game PacMap. Openness and portability have been the main design objectives for PacMap. We elaborate on programming techniques which may be applicable to a broad range of location-based games that ...
Chatzidimitris, Thomas, Gavalas, Damianos, Kasapakis, Vlasios   +2 more
core   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

COMPASS - a facility to study QCD

, 2011
An overview on the new COMPASS II experimental programme is presented. The main topics include a study of Primakoff reactions, generalised parton distributions via deeply virtual Compton scattering and transverse momentum dependent distributions in Drell-
Kabuss, Eva-Maria
core  

Deeply Virtual Compton Scattering at JLab Hall A

, 2006
The deeply virtual Compton scattering reaction has been investigated in the Hall A of the Jefferson Laboratory by measuring longitudinally polarized (e,e'gamma) cross sections, in the valence quark region, for protons and neutrons. In the proton channel,
Voutier, Eric
core   +3 more sources

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
ABSTRACT This special issue marking the University of Bath's 60th anniversary offers an opportunity to reflect on nearly a decade of research into the evolution of gene regulatory networks (GRNs) from members of the lab and elsewhere. Our goal is to understand how GRNs rewire and how new transcription factor (TF) functions evolve. Using an experimental
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source