Results 151 to 160 of about 8,210 (263)

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo   +5 more
wiley   +1 more source

Fully Quantum Perturbative Description of Correlated Stokes–Anti‐Stokes Scattering

open access: yesphysica status solidi (b), EarlyView.
The generation of Stokes‐anti‐Stokes (SaS) photon pairs with quantum correlations, like entanglement, has been developing recently, but a proper theoretical ground was missing. A fully quantum perturbative theory is provided to describe the four‐wave mixing contribution to the correlated SaS scattering, in which both matter and electromagnetic field ...
Raul Corrêa   +3 more
wiley   +1 more source

PID‐Like Robust Control of Non‐Minimum Phase Robotic Manipulators

open access: yesInternational Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT This paper proposes an output‐feedback tracking controller for non‐minimum phase nonlinear systems with unknown uncertainties and external disturbances, where not all states are measurable, and the zero dynamics are unstable. The approach combines a backstepping‐based stabilizing state‐feedback law with a cascade extended high‐gain observer ...
Mohammad Al Saaideh   +2 more
wiley   +1 more source

Deep Reinforcement Learning‐Based Control for Real‐Time Hybrid Simulation of Civil Structures

open access: yesInternational Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT Real‐time Hybrid Simulation (RTHS) is a cyber‐physical technique that studies the dynamic behavior of a system by combining physical and numerical components that are coupled through a boundary condition enforcer. In structural engineering, the numerical components are subjected to environmental loads that become dynamic displacements of the ...
Andrés Felipe Niño   +6 more
wiley   +1 more source

CONCERT: A Modular Reconfigurable Robot for Construction

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT This paper presents CONCERT, a fully reconfigurable modular collaborative robot (cobot) for multiple on‐site operations in a construction site. CONCERT has been designed to support human activities in construction sites by leveraging two main characteristics: high‐power density motors and modularity. In this way, the robot is able to perform a
Luca Rossini   +18 more
wiley   +1 more source

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