Advanced Science, EarlyView.Computational Photochemistry has made great strides in recent decades, but the investigation of larger molecules remains a challenge due to the inherent dilemma between the increasing computational accuracy required as the molecule size increases and the inevitable explosion in computational effort.
Andreas Dreuw
wiley +1 more source
Interaction Rituals in a Virtual Learning Environment
, 2022 Andy Aydın‐Aitchison
openalex +1 more source
Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery
Advanced Science, EarlyView.Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra +6 more
wiley +1 more source
Experiences and outcomes of craft skill learning with a 360° virtual learning environment and a head-mounted display. [PDF]
Heliyon, 2020 Hallberg S, Hirsto L, Kaasinen J.
europepmc +1 more source
Physics‐Embedded Neural Network: A Novel Approach to Design Polymeric Materials
Advanced Science, EarlyView.Traditional black‐box models for polymer mechanics rely solely on data and lack physical interpretability. This work presents a physics‐embedded neural network (PENN) that integrates constitutive equations into machine learning. The approach ensures reliable stress predictions, provides interpretable parameters, and enables performance‐driven, inverse ...
Siqi Zhan +8 more
wiley +1 more source
NETWORKED LEARNING PHYSICS OF SEMICONDUCTORS THROUGH A VIRTUAL LABORATORY ENVIRONMENT
, 2010 Κωνσταντίνος Νίνος +4 more
openalex +1 more source
ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology
Advanced Science, EarlyView.This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li +25 more
wiley +1 more source
VIRTUAL LEARNING ENVIRONMENT IN PEDIATRIC RHEUMATOLOGY FOR PEDIATRIC RESIDENTS. [PDF]
Rev Paul Pediatr, 2020 Cunha ALG, Terreri MT, Len CA.
europepmc +1 more source
3D Interactive virtual environments for E-learning, teaching and technical support: Multiplayer teaching and learning games for the School of Art, Design & Architecture. [PDF]
This paper outlines the key stages of a University funded teaching and learning project, the main objective of the project is to build an online 3D virtual Ramsden workshop (RW) game learning environment.
Cunningham, Paul +2 more
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