Results 141 to 150 of about 9,294,963 (257)

Gabapentin as an add‐on analgesic to morphine in paediatric patients with chronic pain

British Journal of Clinical Pharmacology, EarlyView.
Aims Off‐label use of gabapentin for the treatment of chronic pain in children has increased over the last decade, with multiple clinical trials evaluating its role pain management and potential opioid‐sparing effects. To date, however, these studies appear to rely on empirical evidence without further consideration of pharmacokinetic‐pharmacodynamic ...
Paul Healy, Mariagrazia Felisi, Adriana Ceci, Oscar Della Pasqua, on Behalf of the GAPP Consortium, Corinne Alberti, Donato Bonifazi, Adriana Ceci, Thomas G. de Leeuw, Saskia N. de Wildt, Mariagrazia Felisi, Florentia Kaguelidou, Enora Le Roux, Rebecca Lundin, Laura Mangiarini, Dick Tibboel   +15 more
wiley   +1 more source

Widening participation and the changing risks of higher education: Working‐class women's pathways via access courses across two decades

British Educational Research Journal, EarlyView.
Abstract Widening participation (WP) in higher education (HE) remains a central concern within UK educational and social policy. It seeks to address the underrepresentation of specific social groups by tailoring university access to their distinct needs.
Sarah McLaughlin, Richard Waller
wiley   +1 more source

Stand-alone virtual reality exposure therapy as a treatment for social anxiety symptoms: a systematic review and meta-analysis. [PDF]

Ups J Med Sci, 2023
Rejbrand C, Fure B, Sonnby K.
europepmc   +1 more source

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

Biotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga, Udisha Singh, Sachin Dattram Pawar   +2 more
wiley   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

Retrieval Practice Through an Integrated Anatomy Laboratory Experience in a Doctor of Physical Therapy Curriculum

Clinical Anatomy, EarlyView.
ABSTRACT Gross anatomy is a foundational first‐year component of Doctor of Physical Therapy (DPT) curriculum, with limited future vertical integration. Retrieval practice and spaced learning to enhance retention are rarely embedded in second‐year DPT coursework.
Christina M. Cuka, Kellie C. Huxel Bliven, Emilio J. Puentedura   +2 more
wiley   +1 more source

Virtual reality exposure therapy for reducing social anxiety in stuttering: A randomized controlled pilot trial. [PDF]

Front Digit Health, 2023
Chard I, Van Zalk N, Picinali L.
europepmc   +1 more source

Using Anatomy to Prepare Healthcare Students for Patient Death: A Systematic Review

Clinical Anatomy, EarlyView.
ABSTRACT Healthcare students frequently encounter death in clinical practice, yet formal curricula may not appropriately prepare them for its emotional and ethical challenges. Anatomy education using human body donors has the potential to provide early, structured exposure to death, potentially shaping professional, cognitive, and emotional ...
Lucy C. Cowperthwaite, Kat A. Sanders, Steph Busby   +2 more
wiley   +1 more source

Internet-Based Cognitive Behavioral Therapy and Virtual Reality Exposure Therapy for Social Anxiety Disorder: Protocol for a Randomized Controlled Trial in Hong Kong. [PDF]

JMIR Res Protoc, 2023
Pan JY.
europepmc   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source