Results 51 to 60 of about 9,294,963 (257)

UgrA in VR : a virtual reality simulation for training anaesthetists

, 2021
We present a virtual reality training simulator for medical interns practicing ultrasound-guided regional anaesthesia (UGRA). UGRA is a type of nerve block procedure performed commonly by critical care doctors such as anaesthetists, emergency medicine ...
Bogdanovych, Anton (R13982), Chuan, Alwin   +1 more
core   +1 more source

USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

Advanced Science, EarlyView.
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui, Yuanlong Hu, Lin Lin, Lei Zhang, Chao Li, Yunlun Li   +5 more
wiley   +1 more source

Effects of Exergames and Resistance Training on Well-Being in Older Adults: A Randomized Clinical Trial [PDF]

Geriatrics, Gerontology and Aging
OBJECTIVE: To analyze the effects of an exergame-based training compared to resistance training on the quality of life and symptoms of depression in older adults. METHODS: This was a two-arm, non-blinded, randomized clinical trial.
Vandrize Meneghini, Eduardo Hauser, Camilo Luis Monteiro Lourenço, Aline Rodrigues Barbosa   +3 more
doaj   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

Mental health clients’ perspectives on telehealth-based virtual reality therapy

Frontiers in Virtual Reality
There is growing need for better mental health care. It is now possible to combine convenient telehealth with engaging virtual reality towards new opportunities for personalized mental health.
Triton Ong, Julia Ivanova, Hiral Soni, Janelle Barrera, Janelle Barrera, Mollie Cummins, Mollie Cummins, Brandon M. Welch, Brandon M. Welch, Brian E. Bunnell, Brian E. Bunnell   +10 more
doaj   +1 more source

Can the learning of laparoscopic skills be quantified by the measurements of skill parameters performed in a virtual reality simulator?

International Brazilian Journal of Urology, 2013
Purpose To ensure patient safety and surgical efficiency, much emphasis has been placed on the training of laparoscopic skills using virtual reality simulators.
Natascha Silva Sandy, Jose Arnaldo Shiomi da Cruz, Carlo Camargo Passerotti, Hiep Nguyen, Sabrina Thalita dos Reis, Eder Maxwell Gouveia, Ricardo Jordao Duarte, Homero Bruschini, Miguel Srougi   +8 more
doaj   +1 more source

DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury

Advanced Science, EarlyView.
This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang, Jihong Jiang, Huanxin Yin, Chunyan Liu, Hongjun Huang, Yan Luo, Minmin Zhu, Qiuyun Wang   +7 more
wiley   +1 more source

Cognitive predictors of treatment outcome for exposure therapy: do changes in self-efficacy, self-focused attention, and estimated social costs predict symptom improvement in social anxiety disorder?

BMC Psychiatry, 2019
Background Cognitions play an important role in the development and maintenance of social anxiety disorder (SAD). Methods To investigate whether changes in cognitions during the first six sessions of exposure therapy are associated with treatment outcome,
Isabel L. Kampmann, Paul M. G. Emmelkamp, Nexhmedin Morina   +2 more
doaj   +1 more source

Virtual Reality [PDF]

, 2012
At present, the virtual reality has impact on information organization and management and even changes design principle of information systems, which will make it adapt to application requirements.

core   +1 more source

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

Advanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao, Zimeng Huang, Jianing Gao, Aolan Li, Huizhi Wang, Yingchuan Chen, Guanyu Zhu, Xin Zhang, Yin Jiang, Moxuan Zhang, Fangang Meng, Jianguo Zhang, Tingting Du   +12 more
wiley   +1 more source