Results 91 to 100 of about 863,901 (283)

Normativity and Aristotelian virtue ethics: an evaluation and reconciliation [PDF]

open access: yes
In recent decades, Aristotelian virtue ethics has reemerged as an alternative to deduction-based moral theories. Yet, Aristotelian virtue ethics has often been conceived by its proponents as well as its detractors, as an approach to ethical thinking that
Allard-Nelson, Susan K.
core  

“A Scout Is Trustworthy”: Applying Virtue Ethics to Lawyer Professionalism [PDF]

open access: yes, 2013
This Article advocates the employment of the twelve-point Scout Law of the Boy Scouts of America as a professional ethics guide for lawyers. The Article begins by briefly relating the history of virtue ethics as a philosophical field of study and ...
Justice Jeff Brown, Brown, Jeff
core  

Critique of Virtue Ethics

open access: yes, 2012
In the last few chapters it has been argued that the life of virtue is the best, happiest and most desirable life. Even accepting that, one might wonder whether or not it is possible to have this life. This chapter will address some of those concerns and
Barbro Fröding, Fröding, Barbro,
core   +1 more source

Organic Nanozyme‐Embedded Biotherapeutic Thermosensitive Hydrogel for Extracellular GSH Depletion and Postoperative Tumor Suppression

open access: yesAdvanced Science, EarlyView.
A temperature‐sensitive hydrogel loaded with cyanine nanozymes and Escherichia coli is locally injected into postoperative tumor resection beds. Upon light irradiation, synergistic PTT and PDT work with cascaded reactive oxygen species to deplete extracellular GSH, eliminate residual tumor cells, and induce robust antitumor immune responses for ...
Cong Jiang   +10 more
wiley   +1 more source

Wady środowiskowe jako etyczne i antropologiczne źródła kryzysu środowiskowego

open access: yesStudia Ecologiae et Bioethicae, 2014
The root of the environmental crisis is not only the failure to recognize the intrinsic value of the non-human world, but it can also be perceived as a failure in moral excellence and in the cultivation of virtue.
Dominika Dzwonkowska
doaj   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

Towards Computer Simulations of Virtue Ethics

open access: yesOpen Philosophy, 2019
This article presents two approaches for computer simulations of virtue ethics in the context of agent-based modeling, a simple way and a complex way.
Lasquety-Reyes Jeremiah A.
doaj   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

open access: yesAdvanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li   +11 more
wiley   +1 more source

Murdoch’s Platonistic virtue ethics [PDF]

open access: yes, 2014
In this paper I develop a thesis about normative ethics that we might call Platonistic virtue ethics (PVE): Good agency in the truest and fullest sense presupposes the contemplation of the Form of the Good.
Chappell, Timothy
core  

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

open access: yesAdvanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen   +11 more
wiley   +1 more source

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