Results 91 to 100 of about 358,407 (284)
Advanced Science, EarlyView.Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang +9 more
wiley +1 more source
Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI
Advanced Science, EarlyView.ABSTRACT 2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time‐consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal
Pablo Arratia +7 more
wiley +1 more source
Ethics as a political alternative to the control devices
Filosofia Unisinos, 2021 The control societies reduced the person to a struture proceeding to obtain efficient an the institutional objetives. Their control methods make flexivel subjetivities. One alternative to the control dispositives is to ransom the ethics so a praxis that
Castor M. M. Bartolomé Ruiz
doaj
Advanced Science, EarlyView.ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu +20 more
wiley +1 more source
Ethics of Duty vs. Ethics of Virtue in Teacher Training
Paedagogia Christiana, 2011 Given the assumption that a modern teacher’s role cannot just be narrowed down to being an instructor, but that he should also carry out the role of a form tutor providing all necessary care, advice, assistance and support for a maturing person, the ...
Jarosław Horowski
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Advanced Science, EarlyView.The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob +12 more
wiley +1 more source
John Doris' Excellence Adventure
Revista de Filosofia Antiga, 2018 : In his book Lack of Character (2002 Cambridge University Press) John Doris argues that both virtue ethics and common sense or folk psychology are committed to the claim that the attribution of character to persons is predictive, explanatory, and ...
Carrie Swanson
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Quaker Virtue Ethics: Religious Life without Creeds [PDF]
, 2019 Beliefs are conventionally understood to guide people’s actions. Put another way, the actions which people take are understood to be products of what they believe.
Nagaji, Dave
core +1 more source
Advanced Science, EarlyView.This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen +11 more
wiley +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Advanced Science, EarlyView.Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source