Results 81 to 90 of about 28,035 (244)

Self‐Adaptive Allantoin@ZIF8 Nanocomposite Hydrogel with Resveratrol Synergy for MRSA‐Infected Wound Regeneration

open access: yesAdvanced Science, EarlyView.
Based on allantoin‐loaded ZIF8 nanoparticles (Alla@ZIF8) and methacrylated quaternary ammonium carboxymethyl chitosan/resveratrol composite hydrogels (RMQCC), an adaptive multifunctional hydrogel system (Alla@ZIF8‐Gel) was constructed and confirmed to induce the healing of MRSA‐infected wounds via suppressing bacterial proliferation, alleviating ...
Yongjie Zhu   +8 more
wiley   +1 more source

The Relationship between Nasir al-Din al-Tusi’s Moral Theory and the Normative Theories in Contemporary Moral Philosophy with an Emphasis on Virtue Ethics [PDF]

open access: yesاخلاق وحیانی, 2017
The moral theory of Nasir al-Din al-Tusi is an important normative theory in the Islamic philosophical ethics. It is important to update this theory and specify its relationship with other normative theories in contemporary moral philosophy.
Masoomeh Soleiman Meigooni   +1 more
doaj  

H2S‐Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety

open access: yesAdvanced Science, EarlyView.
Albumin nanoparticles loaded with an H2S‐releasing aspirin derivative (ACS14) hitchhiking neutrophils after intraperitoneal injection and preferentially accumulate in endometriosis lesions in mice. The treatment suppresses lesion growth by regulating PI3K/Akt and reduces inflammation by inhibiting NF‐κB.
Mengni Zhou   +12 more
wiley   +1 more source

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

open access: yesAdvanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob   +12 more
wiley   +1 more source

Virtue Ethics in a Value-driven World: Viral Virtues. [PDF]

open access: yesClin Orthop Relat Res, 2022
Humbyrd CJ.
europepmc   +1 more source

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

open access: yesAdvanced Science, EarlyView.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen   +11 more
wiley   +1 more source

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