Results 111 to 120 of about 430,324 (188)

Human Coronavirus Virulence Motifs and Virulence

open access: yes, 2017
We have shown that SARS-CoV E protein is a virulence factor that includes at least two virulence motifs: its ion channel (IC) activity encoded within the transmembrane domain and a PDZ binding motif (PBM) located at its carboxy-terminus. We showed that E protein pathogenicity was caused by the activation of different host signaling pathways.
Enjuanes Sánchez, Luis   +12 more
openaire   +1 more source

Characterization of novel beta-galactosidase activity that contributes to glycoprotein degradation and virulence in Streptococcus pneumoniae.

open access: yes, 2009
The pneumococcus obtains its energy from the metabolism of host glycosides. Therefore, efficient degradation of host glycoproteins is integral to pneumococcal virulence.
Andrew, Peter W   +4 more
core   +2 more sources

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