Results 211 to 220 of about 861,199 (358)

Identifying Virulence Determinants In Pathogenic Mycobacteria Via Changes In Host Cell Mitochondrial Morphology [PDF]

open access: yesarXiv
The goal of this study is to develop a computational model of the progression of changes in mitochondrial phenotype resulting from infection with pathogenic mycobacteria. This ultimately will enable a large-scale virulence screen of mutant bacterial libraries. Mycobacterium tuberculosis (Mtb) is an intracellular pathogen, but only a small number of its
arxiv  

Photo‐controlled Release of Urea Enables the Detection of Urea‐Urease Intermediates by cryo‐FTIR

open access: yesAngewandte Chemie International Edition, Accepted Article.
Caged compounds are a valuable tool to photocontrol the release of enzymatic substrates in a reaction. For example, caged urea molecules were proposed to control urea delivery to urease reactions and aid the determination of the catalytic mechanism of this enzyme.
Caterina Netto   +7 more
wiley   +1 more source

Impact of Salmonella genome rearrangement on gene expression

open access: yesEvolution Letters, Volume 6, Issue 6, Page 426-437, December 2022., 2022
Abstract In addition to nucleotide variation, many bacteria also undergo changes at a much larger scale via rearrangement of their genome structure (GS) around long repeat sequences. These rearrangements result in genome fragments shifting position and/or orientation in the genome without necessarily affecting the underlying nucleotide sequence.
Emma V. Waters   +4 more
wiley   +1 more source

Human brucellosis: recent advances and future challenges

open access: yesInfectious Diseases of Poverty, 2020
David O’Callaghan
doaj   +1 more source

Optimal virulence strategies in epidemiological models with asymptomatic transmission [PDF]

open access: yesarXiv
Asymptomatic infection has gained notoriety as an important feature of infectious disease dynamics. Despite increasing attention, there have been few rigorous examinations of how asymptomatic transmission influences pathogen evolution. In this study, we apply evolutionary invasion analysis to compute optimal strategies for viruses evolving in a system ...
arxiv  

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