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Virulence Attributes of Low‐Virulence Organisms [PDF]
The vast majority of infections involving female pelvic structures arise from organisms that are members of the normal flora. In addition, exogenous organisms that invade through the lower genital tract must interact with organisms that are part of the host′s flora.
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Evolution of virulence in opportunistic pathogens: generalism, plasticity, and control [PDF]
Standard virulence evolution theory assumes that virulence factors are maintained because they aid parasitic exploitation, increasing growth within and/or transmission between hosts. An increasing number of studies now demonstrate that many opportunistic
Brown, Sam P.+2 more
core +1 more source
Biofilms in Diabetic Foot Ulcers: Significance and Clinical Relevance
Foot infections are the main disabling complication in patients with diabetes mellitus. These infections can lead to lower-limb amputation, increasing mortality and decreasing the quality of life. Biofilm formation is an important pathophysiology step in
Cassandra Pouget+5 more
doaj +1 more source
Bacterial Interactions in the Context of Chronic Wound Biofilm: A Review
Chronic wounds, defined by their resistance to care after four weeks, are a major concern, affecting millions of patients every year. They can be divided into three types of lesions: diabetic foot ulcers (DFU), pressure ulcers (PU), and venous/arterial ...
Benjamin A. R. N. Durand+5 more
doaj +1 more source
Virulence and Metabolism [PDF]
ABSTRACT Staphylococcus aureus is clearly the most pathogenic member of the Staphylococcaceae . This is in large part due to the acquisition of an impressive arsenal of virulence factors that are coordinately regulated by a series of dedicated transcription factors.
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Comparative genomics and transcriptomics of Escherichia coli isolates carrying virulence factors of both enteropathogenic and enterotoxigenic E. coli [PDF]
Escherichia coli that are capable of causing human disease are often classified into pathogenic variants (pathovars) based on their virulence gene content. However, disease-associated hybrid E.
Daugherty, Sean C+6 more
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At the close of the 19th century, the germ theory had generated a new understanding of the causes of acute infectious diseases and revealed new directions for study. This understanding contributed to the greatest improvements in health in the history of medicine.
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European starlings are widespread migratory birds that have already been described as carrying bacteria resistant to extended-spectrum cephalosporins (ESC-R). These birds are well known in Tunisia because they spend the wintertime in this country and are
Meriem Souguir+8 more
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Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence [PDF]
Efflux pumps of the resistance-nodulation-cell-division (RND) family increase antibiotic resistance in many bacterial pathogens, representing candidate targets for the development of antibiotic adjuvants.
Baldelli, Valerio+8 more
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Pathogenicity locus, core genome, and accessory gene contributions to Clostridium difficile virulence [PDF]
Clostridium difficile is a spore-forming anaerobic bacterium that causes colitis in patients with disrupted colonic microbiota. While some individuals are asymptomatic C.
Brittany B. Lewis+9 more
core +7 more sources