Results 91 to 100 of about 13,031,687 (355)

Determination of virulence factors and biofilm formation among isolates of vulvovaginal candidiasis

Journal of Medical Sciences, 2016
Context: Under morphogenesis-inducing conditions, Candida spp. begins to undergo yeast-to-hypha switch. This shift from commensal to pathogenic state is dependent on several virulence factors. Aim: To find out whether the isolated Candida spp.
Tapan Majumdar, Jhinuk Basu Mullick, Raunak Bir, Jayanta Roy, Samir Kumar Sil   +4 more
doaj   +1 more source

Virulence factors of Helicobacter pylori

International Journal of Medical Microbiology, 2001
To date a number of virulence factors have been identified and characterised from the gastric pathogen Helicobacter pylori. The vacuolating toxin (VacA) is a major determinant of H. pylori-associated gastric disease. In non-polarised cells, VacA alters the endocytic pathway, resulting in the release of acid hydrolases and the reduction of both ...
DUNDON, WILLIAM GEORGE, DE BERNARD, MARINA, MONTECUCCO, CESARE   +2 more
openaire   +3 more sources

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

Targeting anti-virulence factor strategies of bacterial pathogens

Biosafety and Health
Antibiotic-resistant bacterial pathogens pose substantial biosafety and health hazards, leading to millions of deaths each year. The evolution of bacterial virulence factors is mainly propelled by horizontal gene transfer (HGT).
Jiashu Li, Tianyuan Jia, Liang Yang
doaj   +1 more source

Inhibition of bacterial virulence factors as a method of treating bacterial pneumonia

Zdorovʹe Rebenka, 2018
Incremental increase in the number of antibiotic-resistant bacterial strains in the etiologic structure of pneumonia and reduced potential of antibiotic therapy increase the importance of drugs in the treatment of pneumonia, which are aimed at ...
А.Е. Abaturov, Т.А. Kryuchko
doaj   +1 more source

Nepetin reduces virulence factors expression by targeting ClpP against MRSA-induced pneumonia infection [PDF]

, 2022
Shisong Jing, Xinran Ren, Li Wang, Xiangri Kong, Xingye Wang, Xiren Chang, Xuerui Guo, Yan Shi, Jiyu Guan, Tiedong Wang, Bingmei Wang, Song Wu, Yicheng Zhao   +12 more
openalex   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Pseudomonas Aeruginosa: Virulence Factors and Antibiotic Resistance Genes

Brazilian Archives of Biology and Technology, 2019
In this review, we explore some aspects of Pseudomonas aeruginosa virulence factors that are related to disease development in healthy organisms and resistance to antibiotics.
A. Rocha, Mario R. O. Barsottini, Renan Rhonalty Rocha, Maria Vitória Laurindo, Francisco Leandro Laurindo de Moraes, Soraya Lília da Rocha   +5 more
semanticscholar   +1 more source

Plant Virus‐Induced Inheritable Apoptosis Drives Reproductive Costs in Female Insect Vectors to Balance Viral Biparental Transmission

Advanced Science, EarlyView.
Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu, Wenqiang Wan, Qingquan Liang, Hengsong Yang, Chengcong Lu, Taiyun Wei, Qian Chen   +6 more
wiley   +1 more source

Victors: a web-based knowledge base of virulence factors in human and animal pathogens

Nucleic Acids Res., 2018
Virulence factors (VFs) are molecules that allow microbial pathogens to overcome host defense mechanisms and cause disease in a host. It is critical to study VFs for better understanding microbial pathogenesis and host defense mechanisms. Victors (http://
Samantha Sayers, Li Li, Edison Ong, Shunzhou Deng, Guanghua Fu, Yu Lin, Brian Yang, Xiaoqin Zhang, Zhenzong Fa, Bin Zhao, Zuoshuang Xiang, Yongqing Li, Xing-Ming Zhao, M. Olszewski, Luonan Chen, Y. He   +15 more
semanticscholar   +1 more source