Results 91 to 100 of about 12,773,381 (399)

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Natural quorum sensing inhibitors effectively downregulate gene expression of Pseudomonas aeruginosa virulence factors

Applied Microbiology and Biotechnology, 2019
At present, anti-virulence drugs are being considered as potential therapeutic alternatives and/or adjuvants to currently failing antibiotics. These drugs do not kill bacteria but inhibit virulence factors essential for establishing infection and ...
S. A. S. Ahmed, M. Rudden, T. Smyth, J. Dooley, R. Marchant, I. Banat   +5 more
semanticscholar   +1 more source

Group A Streptococcal S Protein Utilizes Red Blood Cells as Immune Camouflage and Is a Critical Determinant for Immune Evasion. [PDF]

, 2019
Group A Streptococcus (GAS) is a human-specific pathogen that evades the host immune response through the elaboration of multiple virulence factors. Although many of these factors have been studied, numerous proteins encoded by the GAS genome are of ...
Campeau, Anaamika, Dehaini, Diana, Fang, Ronnie H, Gonzalez, David J, Greene, Trever, Holay, Maya, Lamsa, Anne, LaRock, Christopher N, Pogliano, Kit, Sands, Jenna S, Wei, Xiaoli, Wierzbicki, Igor H, Ying, Man, Zhang, Liangfang, Zuniga, Elina   +14 more
core  

High levels of cyclic di-GMP in Klebsiella pneumoniae attenuate virulence in the lung [PDF]

, 2018
The bacterial second messenger bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) has been shown to influence the expression of virulence factors in certain pathogenic bacteria, but little is known about its activity in the increasingly antibiotic-resistant ...
Hunstad, David A, Rosen, David A, Twentyman, Joy   +2 more
core   +2 more sources

Amplification‐Free, Sequencing‐Free, Detection of Viral RNAs with Variant Specification by Discrete Nanocounting

Advanced Functional Materials, EarlyView.
Integrating selective RNA shortcut, targeted gene isolation, and micro‐arrayed nanoimaging, the NanoPick‐array platform excels in detecting severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) at just 60 copies µL−1 and accurately differentiating variants at the single‐nucleotide level. It ensures 100% accuracy for samples with cycle threshold (
Zixun Wang, Xi Zhao, Wan‐Mui Chan, Xianglin Ji, Linfeng Huang, Xi Xie, Wei Li, Wenjun Zhang, Kelvin Kai‐Wang To, Peng Shi   +9 more
wiley   +1 more source

COVID‐19 in the Pacific territories: Isolation, borders and the complexities of governance

Asia &the Pacific Policy Studies, Volume 9, Issue 3, Page 394-407, September 2022., 2022
Abstract Early experience of COVID‐19 in seven Pacific politically dependent territories (Guam, American Samoa, Pitcairn, Tokelau, French Polynesia, Wallis and Futuna, and New Caledonia) emphasises a diversity of contexts, responses, outcomes and possible futures.
John Connell
wiley   +1 more source

Virulence Factors of Clinical and Fecal Isolates of Enterococci Species

Journal of Pure and Applied Microbiology, 2023
Enterococci species are known commensals of the gastrointestinal flora; however, in recent years, they have emerged as important nosocomial pathogens that possess many virulence factors that are attributed to the pathogenesis of diseases caused by them ...
Sudhamani Kumar, U. Purna Chandra Rao, Arvind Natarajan, Sagar Mali, P.M. Beena   +4 more
doaj   +1 more source

Genomic Analysis and Artificial Intelligence: Predicting Viral Mutations and Future Pandemics [PDF]

arXiv, 2023
This study presents a novel approach at the intersection of genomic analysis and artificial intelligence (AI) to predict viral mutations and assess the risks of future pandemics. Through comprehensive genomic analysis, genetic markers associated with increased virulence and transmissibility are identified.
arxiv  

Helicobacter pylori Virulence Factors Exploiting Gastric Colonization and its Pathogenicity

Toxins, 2019
Helicobacter pylori colonizes the gastric epithelial cells of at least half of the world’s population, and it is the strongest risk factor for developing gastric complications like chronic gastritis, ulcer diseases, and gastric cancer.
S. Ansari, Y. Yamaoka
semanticscholar   +1 more source

Draft Genome Sequences of Salmonella enterica Serovar Typhimurium LT2 with Deleted Chitinases That Are Emerging Virulence Factors. [PDF]

, 2017
Chitinases are glycosyl hydrolases that catalyze the hydrolysis of the β-1,4 linkages in complex carbohydrates and those that contain GlcNAc. These enzymes are considered emerging virulence factors during infection because the host glycan changes.
Arabyan, Narine, Huang, Bihua C, Weimer, Bart C   +2 more
core   +1 more source