Comparative genomics and transcriptomics of Escherichia coli isolates carrying virulence factors of both enteropathogenic and enterotoxigenic E. coli [PDF]
Escherichia coli that are capable of causing human disease are often classified into pathogenic variants (pathovars) based on their virulence gene content. However, disease-associated hybrid E.
Daugherty, Sean C+6 more
core +2 more sources
Introduction: Extended-spectrum β-lactamase producing commensal Escherichia coli are considered as a reservoir of antibiotic resistance genes that may be transmitted in the community.
Salesh P Chandran+7 more
doaj +1 more source
Detection of virulence factors and beta-lactamase encoding genes among the clinical isolates of Pseudomonas aeruginosa [PDF]
Background: Pseudomonas aeruginosa has emerged as a significant opportunistic bacterial pathogen that causes nosocomial infections in healthcare settings resulting in treatment failure throughout the world. This study was carried out to compare the relatedness between virulence characteristics and \b{eta}-lactamase encoding genes producing Pseudomonas ...
arxiv +1 more source
When is a bacterial “virulence factor” really virulent? [PDF]
ABSTRACTBacterial traits that contribute to disease are termed ‘virulence factors’ and there is much interest in therapeutic approaches that disrupt such traits. However, ecological theory predicts disease severity to be multifactorial and context dependent, which might complicate our efforts to identify the most generally important virulence factors ...
Granato, Elisa T.+3 more
openaire +2 more sources
Phosphorylation of CFP10 modulates Mycobacterium tuberculosis virulence
Virulence effectors secreted by Mycobacterium tuberculosis (Mtb) help subvert host immune mechanisms and, therefore, are critical for establishing infection and pathogenesis. However, knowledge in terms of signaling mechanisms that modulate the secretion
Basanti Malakar+9 more
doaj +1 more source
Cutibacterium acnes as an Opportunistic Pathogen: An Update of Its Virulence-Associated Factors
Cutibacterium acnes is a member of the skin microbiota found predominantly in regions rich in sebaceous glands. It is involved in maintaining healthy skin and has long been considered a commensal bacterium.
C. Mayslich, P. Grange, N. Dupin
semanticscholar +1 more source
What is a virulence factor? [PDF]
Bacterial virulence factors enable a host to replicate and disseminate within a host in part by subverting or eluding host defenses. The use of genomic techniques has led to the identification of new virulence factors that may serve as targets for new therapies.
openaire +2 more sources
The Composition and Spatial Patterns of Bacterial Virulence Factors and Antibiotic Resistance Genes in 19 Wastewater Treatment Plants. [PDF]
Bacterial pathogenicity and antibiotic resistance are of concern for environmental safety and public health. Accumulating evidence suggests that wastewater treatment plants (WWTPs) are as an important sink and source of pathogens and antibiotic ...
Bing Zhang+6 more
doaj +1 more source
Differential inflammatory response to Helicobacter pylori infection: etiology and clinical outcomes [PDF]
The bacterial pathogen Helicobacter pylori commonly colonizes the human gastric mucosa during early childhood and persists throughout life. The organism has evolved multiple mechanisms for evading clearance by the immune system and, despite inducing ...
Robinson, K, White, JR, Winter, JA
core +1 more source
Genome characterization and population genetic structure of the zoonotic pathogen, streptococcus canis [PDF]
Background - Streptococcus canis is an important opportunistic pathogen of dogs and cats that can also infect a wide range of additional mammals including cows where it can cause mastitis. It is also an emerging human pathogen.
Lang, P.+8 more
core +3 more sources