Results 21 to 30 of about 7,877,120 (257)

Parasite variation and the evolution of virulence in a Daphnia-microparasite system [PDF]

, 2008
Understanding genetic relationships amongst the life-history traits of parasites is crucial for testing hypotheses on the evolution of virulence. This study therefore examined variation between parasite isolates (the bacterium Pasteuria ramosa) from the ...
Little, T. J., Chadwick, W., Watt, K.
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Steps toward broad-spectrum therapeutics : discovering virulence-associated genes present in diverse human pathogens [PDF]

, 2009
© 2009 Stubben et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Gans, Jason D, Wolinsky Murray, Cooper, Ian A, Karlyshev, Andrey, Wren, Brendan W, Cooper Ian A, Duffield Melanie L, Ford Donna C, Lingard, Bryan, Ford, Donna C, Oyston, Petra CF, Karlyshev, Andrey V, Titball, Rick W, Lingard, Brian, Duffield, Melanie L, Karlyshev Andrey V, Gans Jason D, Oyston Petra CF, Song, Jian, Stubben, Chris J, Oyston, Petra C F, Titball Rick W, de Rochefort Anna, Stubben Chris J, Wren Brendan W, Lingard Bryan, Wolinsky, Murray, de Rochefort, Anna, Song Jian, Murray Wolinsky, Jason D Gans, Rick W Titball, Brendan W Wren, Donna C Ford, Ian A Cooper, Melanie L Duffield, Andrey V Karlyshev, Petra CF Oyston, Bryan Lingard, Anna de Rochefort, Chris J Stubben, Jian Song   +41 more
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High-throughput genomic and proteomic interpretation of gene duplication in Vibrio cholera genomes: An in silico study

Informatics in Medicine Unlocked, 2023
Background: Vibrio cholerae leads to severe acute watery diarrhea with a high mortality rate; owing to several virulence factors, especially the cholera toxin.
Narjes Noori Goodarzi, Farzad Badmasti, Fatemeh Haririzadeh Jouriani, Sepideh Fereshteh   +3 more
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Pathogenicity and Virulence Factors of Fusarium graminearum Including Factors Discovered Using Next Generation Sequencing Technologies and Proteomics

Microorganisms, 2020
Fusarium graminearum is a devasting mycotoxin-producing pathogen of grain crops. F. graminearum has been extensively studied to understand its pathogenicity and virulence factors.
Molemi E. Rauwane, Udoka V. Ogugua, Chimdi M. Kalu, Lesiba K. Ledwaba, Adugna A. Woldesemayat, Khayalethu Ntushelo   +5 more
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Predicting the virulence of MRSA from its genome sequence [PDF]

, 2014
This work is supported by the EC-FP7 program no. 245500 and the BBSRCMicrobial virulence is a complex and often multifactorial phenotype, intricately linked to a pathogen's evolutionary trajectory.
Josefsson, Elisabet,, Hawkins, E., Josefsson, Elisabet, Holden, M., Yajjala, Vijaya Kumar, Feil, E. J., Read, T. D., Recker, Mario, Rudkin, Justine K., P. D. Fey, Z. Gulay, Kumar Yajjala, Vijaya, Wilson, D., E. J. Feil, Williams, P., T. Widhelm, Sloan, Tim J, Fey, P. D., Gulay, Zeynep, Parfett, S., Gulay, Z., Endres, Jennifer L, M. Recker, Priest, Nicholas K, Hurst, Laurence D, E. Josefsson, Lewis, K., Fey, Paul D, Sloan, Tim J., van den Elsen, J., M. Laabei, Peacock, Sharon J., Priest, Nicholas K., Feil, Edward J., Read, Timothy D., Aldeljawi, Mona, Parfett, Sara, J. K. Rudkin, L. Scowen, Hurst, Laurence D., P. Williams, Widhelm, Todd, S. Parfett, J. L. Endres, N. K. Priest, S. J. Peacock, Massey, R. C., Holden, Matthew, Peacock, Sharon J, J. van den Elsen, Bayles, Kenneth W., M. Holden, Massey, Ruth C., Scowen, L., Feil, Edward J, Rudkin, J. K., Hurst, L. D., E. Hawkins, M. Aldeljawi, Rudkin, Justine K, Read, Timothy D, K. W. Bayles, V. K. Yajjala, Wilson, Daniel, T. J. Sloan, L. D. Hurst, Recker, M., Aldeljawi, M., D. Wilson, Bayles, K. W., Laabei, Maisem, K. Lewis, Bayles, Kenneth W, Scowen, Lucy, Endres, J. L., Laabei, M., Hawkins, Erica, Yajjala, V. K., Williams, Paul, Sloan, T. J., Massey, Ruth C, Lewis, Katie, Endres, Jennifer L., Fey, Paul D., Peacock, S. J., Priest, N. K., van den Elsen, Jean, R. C. Massey, T. D. Read, Widhelm, T., Holden, Matthew; id_orcid   +90 more
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Evolutionary trade-offs underlie the multi-faceted virulence of Staphylococcus aureus [PDF]

, 2015
Date of Acceptance: 20/07/2015Bacterial virulence is a multifaceted trait where the interactions between pathogen and host factors affect the severity and outcome of the infection. Toxin secretion is central to the biology of many bacterial pathogens and
Williams, Barnabas, Uhlemann, Anne-Catrin, Edward Feil, Recker, Mario, Maisem Laabei (311431), Janina Dordel (250569), Janina Dordel, Votintseva, Antonina A., Lowy, Franklin D., Wilson, Daniel J, Bowden, Rory, Wilson, Daniel J., Daniel J. Wilson (194149), Matthew Holden, Crook, Derrick W., Dordel, Janina, Derrick W Crook, Maho Yokoyama (791513), Thorpe, Harry A, Holden, Matthew, Matthew Holden (791517), Sharon J. Peacock (35782), Derrick W. Crook (145636), Austin, Eloise D, Mario Recker (88496), Sharon J Peacock, Eloise D Austin, Perkins, Mark, Votintseva, Antonina A, Barnabas Williams (791515), Mario Recker, Franklin D Lowy, Young, Bernadette C, Khadija Ouadi, Ouadi, Khadija, Eloise D. Austin (791512), Rory Bowden (179995), Barnabas Williams, Bernadette C Young, Maho Yokoyama, Yokoyama, Maho, Clark, Stephen Robert, Harry A Thorpe, Franklin D. Lowy (299074), Edward Feil (270047), Anne-Catrin Uhlemann, Stephen R Clarke, Antonina A Votintseva, Clarke, Stephen R, Peacock, Sharon J., Mark Perkins, Ruth C. Massey (174217), Maisem Laabei, Antonina A. Votintseva (791518), Harry A. Thorpe (791514), Austin, Eloise D., Peacock, Sharon J, Massey, Ruth C., Mark Perkins (254177), Bernadette C. Young (408943), Feil, Edward, Anne-Catrin Uhlemann (299063), Crook, Derrick W, Laabei, Maisem, Khadija Ouadi (598087), Lowy, Franklin D, Daniel J Wilson, Rory Bowden, Stephen R. Clarke (791516), Massey, Ruth C, Young, Bernadette C., Thorpe, Harry A., Ruth C Massey, Austin Eloise D., Recker Mario, Young Bernadette C., Clarke Stephen R., Laabei Maisem, Bowden Rory, Wilson Daniel J., Dordel Janina, Holden Matthew, Crook Derrick W., Ouadi Khadija, Lowy Franklin D., Williams Barnabas, Peacock Sharon J., Feil Edward, Votintseva Antonina A., Thorpe Harry A., Perkins Mark, Uhlemann Anne-Catrin, Yokoyama Maho, Massey Ruth C., Holden, Matthew; id_orcid   +94 more
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Gac two-component system in Pseudomonas syringae pv. tabaci is required for virulence but not for hypersensitive reaction [PDF]

, 2008
Pseudomonas syringae pv. tabaci 6605 causes wildfire disease on host tobacco plants. To investigate the regulatory mechanism of the expression of virulence, Gac two-Component system-defective mutants, Delta gacA and Delta gacS, and a double mutant, Delta
Ichinose, Yuki, Marutani, Mizuri, Ogawa, Yujiro, Yoshishige, Inagaki, Toyoda, Kazuhiro, Shiraishi, Tomonori, Taguchi, Fumiko, Hossain, Mijan Md.   +7 more
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Phosphorylation of CFP10 modulates Mycobacterium tuberculosis virulence

mBio, 2023
Virulence effectors secreted by Mycobacterium tuberculosis (Mtb) help subvert host immune mechanisms and, therefore, are critical for establishing infection and pathogenesis. However, knowledge in terms of signaling mechanisms that modulate the secretion
Basanti Malakar, Komal Chauhan, Priyadarshini Sanyal, Saba Naz, Haroon Kalam, R. P. Vivek-Ananth, Lakshya Veer Singh, Areejit Samal, Dhiraj Kumar, Vinay Kumar Nandicoori   +9 more
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The KdpD/KdpE two-component system : integrating K+ homeostasis and virulence [PDF]

, 2013
The two-component system (TCS) KdpD/KdpE, extensively studied for its regulatory role in potassium (K+) transport, has more recently been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria ...
Freeman, Zoë N., Zoë N Freeman, Steve Dorus, Waterfield, Nicholas R., Dorus, Steve, Nicholas R Waterfield   +5 more
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Streptococcus suis pathogenesis—A diverse array of virulence factors for a zoonotic lifestyle

, 2021
Streptococcus suis is a major cause of respiratory tract and invasive infections in pigs and is responsible for a substantial disease burden in the pig industry. S. suis is also a significant cause of bacterial meningitis in humans, particularly in South
Atack, JM, Patrick J. Blackall, Tram, G, Michael P. Jennings, John M. Atack, Greg Tram, Jennings, MP, Blackall, PJ   +7 more
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