Results 121 to 130 of about 5,329,833 (353)

An expanded multilocus sequence typing scheme for propionibacterium acnes : investigation of 'pathogenic', 'commensal' and antibiotic resistant strains [PDF]

, 2012
The Gram-positive bacterium Propionibacterium acnes is a member of the normal human skin microbiota and is associated with various infections and clinical conditions.
Barnard, E. (Emma), Cove, Jonathan, Eady, Anne, Gao, Anna, Li, Huiying, McDowell, A. (Andrew), Nagy, I. (István), Nord, Carl Erik, Patrick, Sheila, Tomida, Shuta   +9 more
core   +3 more sources

Phage-mediated Dispersal of Biofilm and Distribution of Bacterial Virulence Genes Is Induced by Quorum Sensing

PLoS Pathogens, 2015
The microbiome and the phage meta-genome within the human gut are influenced by antibiotic treatments. Identifying a novel mechanism, here we demonstrate that bacteria use the universal communication molecule AI-2 to induce virulence genes and transfer ...
Friederike S. Rossmann, T. Racek, D. Wobser, J. Puchalka, Elaine M. Rabener, Matthias Reiger, A. Hendrickx, Ann-Kristin Diederich, K. Jung, C. Klein, J. Huebner   +10 more
semanticscholar   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Monitoring the Dutch Phytophtora infestans population for virulence against new R-genes [PDF]

New possibilities offered by marker assisted breeding and GMO breeding have sparked renewed international efforts to breed for durable potato late blight resistance.
Bekkum, P.J., van, Bosch, G.B.M., van den, Evenhuis, A., Förch, M.G., Vossen, J.H.   +4 more
core   +1 more source

Uropathogenic Escherichia coli virulence genes: invaluable approaches for designing DNA microarray probes

Central European Journal of Urology, 2015
Introduction The pathotypes of uropathogenic Escherichia coli (UPEC) cause different types of urinary tract infections (UTIs). The presence of a wide range of virulence genes in UPEC enables us to design appropriate DNA microarray probes.
Nadia Jahandeh, R. Ranjbar, P. Behzadi, E. Behzadi   +3 more
semanticscholar   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Correlation between antimicrobial resistance and virulence in carbapenem-resistant Klebsiella pneumoniae at colonization and infection stages

BMC Infectious Diseases
Objective Carbapenem-resistant Klebsiella pneumoniae (CRKP) has emerged as a critical global public health. To investigate the dynamic changes of drug resistance genes and virulence traits in carbapenem-resistant Klebsiella pneumoniae during colonization-
Junning He, Yijie Yin, Cheng Li, Ning Xie, Peilin Zhang, Guixia Wang, Xianting Liang, Yongfang Liu   +7 more
doaj   +1 more source

Gac two-component system in Pseudomonas syringae pv. tabaci is required for virulence but not for hypersensitive reaction [PDF]

, 2008
Pseudomonas syringae pv. tabaci 6605 causes wildfire disease on host tobacco plants. To investigate the regulatory mechanism of the expression of virulence, Gac two-Component system-defective mutants, Delta gacA and Delta gacS, and a double mutant, Delta
A Bultreys, A Chatterjee, A Schaefer, A Stintzi, B Quinones, B Quinones, C Fuqua, DK Willis, EO King, F Taguchi, F Taguchi, Fumiko Taguchi, J Yu, JW Costerton, Kazuhiro Toyoda, KH McClean, LM Keith, M Castaneda, M Elasri, M Marutani, MD Parkins, Md. Mijan Hossain, MF Alexeyev, Mizuri Marutani, NT Keen, PD Shaw, S Heeb, SL Lopez-Garcia, SM Kirov, ST Chancey, T Kitten, TG Kinscherf, TM Barta, Tomonori Shiraishi, WF Fett, Y Ishiga, Yoshishige Inagaki, Yujiro Ogawa, Yuki Ichinose   +38 more
core   +1 more source

Enterohemorrhagic Escherichia coli Virulence Gene Regulation

Microbiology Spectrum, 2014
ABSTRACT Coordinated expression of enterohemorrhagic Escherichia coli virulence genes enables the bacterium to cause hemorrhagic colitis and the complication known as hemolytic-uremic syndrome. Horizontally acquired genes and those common to E. coli contribute to the disease process,
Jay L, Mellies, Emily, Lorenzen
openaire   +2 more sources

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source