The emergence of NDM-1, IMP-7, IMP-26, IMP-62, IMP-76, VIM-4 and VIM-5 producing Pseudomonas aeruginosa strains, identification of a novel sequence type (ST3891) and analysis of virulence genes from a Malaysian tertiary hospital. [PDF]
Kalai Chelvam K +6 more
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Identification of virulence genes and clade-specific markers through pan-genomic analysis of Leptospira. [PDF]
Abdullah M +5 more
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Molecular Epidemiology and Genetic Profile of Non-Typhoidal Salmonella Serovars Isolated From Poultry Production Chain in Khorasan Province, Iran: A Comprehensive Analysis of Prevalence, Virulence Genes, and Antibiotic Resistance. [PDF]
Zavari A, Badouei MA, Tabar GH.
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Virulence genes of poxviruses and reoviruses
Vaccine, 1988Identification of viral genes that specify virulence, however defined, is of critical importance for the design of viral vaccines. In particular, the targeted development not only of avirulent vaccine strains but also of viruses to be used as carriers for foreign genes depends on the inactivation or deletion of genes that harm the host.
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Virulence gene expression in vivo
Current Opinion in Microbiology, 2004The ability to identify and isolate bacterial RNA from animals or humans with infections has markedly advanced the capacity to examine microbial gene expression in vivo. This advance has been coupled with the development of quantitative real-time reverse transcription polymerase chain reaction and expression microarrays to allow investigators to ...
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In search of tuberculosis virulence genes
Trends in Microbiology, 1996The identity of the virulence genes that enable tuberculosis organisms to survive in macrophages and to induce the features of tuberculosis remains largely unknown. Numerous putative virulence genes have been identified, but so far there is only conclusive evidence for the role of two genes, KatG and rpoV, in virulence.
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CRISPR Gene Editing of a Virulent Bacteriophage
Cold Spring Harbor Protocols, 2023Genome editing by site-directed mutagenesis is an important tool in biological research. CRISPR gene editing is the latest such tool developed, and one that is widely applicable to study organisms from all kingdoms of life. Here, I introduce a method for making site-directed, defined mutations in a virulent bacteriophage (a bacterial virus) using ...
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Genes controlling retroviral virulence
1997Publisher Summary Retroviruses under normal circumstances infect cells and yet inflict relatively little damage to the infected cell. The cell, however, remains infected for the lifespan of that cell or any daughter cells derived from that infected cell.
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Defining Virulence Genes in the Dimorphic Fungi
Annual Review of Microbiology, 2006Most dimorphic fungal pathogens cause respiratory disease in mammals and must therefore possess virulence mechanisms to combat and overcome host pulmonary defenses. Over the past decade, advances in genetic tools have made it possible to investigate the basis of dimorphic fungal pathogenesis at the molecular level. Gene disruptions and RNA interference
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Molecular analysis of spv virulence genes of the salmonella virulence plasmids
Molecular Microbiology, 1993SummaryGenes on an 8 kb region common to the virulence plasmids of several serovars of Salmonella are sufficient to replace the entire plasmid in enabling systemic infection in animal models. This virulence region encompasses five genes which previously have been designated with different names from each investigating laboratory.
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