Results 221 to 230 of about 2,134,385 (307)

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez   +13 more
wiley   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima   +6 more
wiley   +1 more source

Evolutionary trade‐offs between beauvericin production and growth define divergent virulence strategies in Beauveria

open access: yesPest Management Science, EarlyView.
Two virulence strategies in Beauveria: a growth strategy characterized by rapid within‐host proliferation, and a toxin strategy involving antimicrobial activity and toxicity to insects Abstract BACKGROUND Pathogen virulence is often attributed to toxin production, yet toxins are metabolically costly and may not universally enhance fitness.
Shasha Hu   +3 more
wiley   +1 more source

Comprehensive profiling of antibiotic resistance, virulence genes, and mobile genetic elements in the gut microbiome of Tibetan antelopes. [PDF]

open access: yesmSystems
Liu J   +17 more
europepmc   +1 more source

Redefining Acne as a Distinct Inflammatory Disease: Acne Is Not an Aesthetic Issue

open access: yes
JEADV Clinical Practice, EarlyView.
Jean Paul Claudel   +4 more
wiley   +1 more source

Discovery of edodine, a natural compound from Lentinula edodes with antibacterial activity for the biological control of fire blight pathogen Erwinia amylovora

open access: yesPest Management Science, EarlyView.
Novel edodine was identified from Lentinula edodes HK761, exhibiting biocontrol potential against fire blight by affecting motility, intracellular ATP level, and cell division of Erwinia amylovora. Abstract BACKGROUND In the search for biological resources with antibacterial activity against Erwinia amylovora, the culture filtrate of Lentinula edodes ...
Yeong Seok Kim   +7 more
wiley   +1 more source

Presence and abundance of airborne Botryosphaeriaceae conidia are governed by temperature and season in the Okanagan Valley, Canada

open access: yesPest Management Science, EarlyView.
Presence and abundance of Botryosphaeria dieback inoculum were determined using spore trapping and droplet digital polymerase chain reaction in British Columbia, Canada. Highest inoculum was recorded in spring (April–June) and again in summer (July–September). These results suggest early pruning in December–January can mitigate pruning wound infections.
Isidora Silva‐Valderrama   +5 more
wiley   +1 more source

Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus

open access: yesPest Management Science, EarlyView.
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano   +7 more
wiley   +1 more source

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