Plasmid-linked virulence genes and high-level gentamicin resistance in <i>Enterococcus faecalis</i> from persistent endodontic infections. [PDF]
Castillo-Guevara A +5 more
europepmc +1 more source
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
Integrative profiling of <i>Helicobacter pylori</i> clinical isolates: virulence genes, antimicrobial susceptibility and genetic diversity in gastric cancer risk stratification. [PDF]
Zhang Y +10 more
europepmc +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Pathogen virulence genes: Advances, challenges and future directions in infectious disease research (Review). [PDF]
Chen Y +8 more
europepmc +1 more source
The fungal effector UvDUF1 from Ustilaginoidea virens not only promotes infection but also acts as a plant immunity elicitor, inducing broad‐spectrum disease resistance in rice and Nicotiana benthamiana. These results reveal its potential as a novel target for sustainable crop protection strategies.
Shuchen Wang +13 more
wiley +1 more source
Evidence of anthrax virulence genes in Bacillus aerius and human exposure in largest abattoir in Lagos, Nigeria. [PDF]
Bamidele TA +13 more
europepmc +1 more source
This review highlights how Phytophthora sojae utilizes unconventional lineage‐specific signaling networks, including unique G protein‐coupled receptor fusions, expanded kinases, and rapidly evolving effectors, to infect soybeans. Understanding these divergent molecular paradigms reveals critical vulnerabilities in this destructive pathogen, offering ...
Min Qiu +4 more
wiley +1 more source
Key virulence genes associated with <i>Streptococcus mutans</i> biofilm formation: a systematic review. [PDF]
Fitri DK +5 more
europepmc +1 more source
Biosurfactant was produced by Pseudomonas aeruginosa using andiroba waste from Amazonia. A biosurfactant–alginate composite (Alg/BioS) was successfully synthesized via ionotropic gelation, and achieved up to 70% Cr6+ removal from water. Abstract Environmental contamination by heavy metals represents a significant challenge due to their persistence in ...
Paulo Diniz Austriaco +11 more
wiley +1 more source

