Results 191 to 200 of about 2,134,385 (307)

Metagenomic and culture‐based insights into host and plasmid contexts of high‐risk ARGs in poultry farm environments

open access: yesiMetaOmics, EarlyView.
Shotgun metagenomics and culture‐based isolate genomics revealed position‐associated high‐risk antibiotic resistance genes (ARGs) signals across poultry manure piles and surrounding soils. Culture‐confirmed Enterobacteriaceae and IncHI2A‐related blaNDM‐5 plasmid backgrounds further highlight priority host‐ARG‐plasmid contexts for farm antimicrobial ...
Yaling Wang   +5 more
wiley   +1 more source

Chicken‐linked multidrug‐resistant Campylobacter jejuni infections among Chinese children

open access: yesiMetaOmics, EarlyView.
Campylobacter is a leading cause of pediatric diarrhea, but its genomic epidemiology and antimicrobial resistance in China remain poorly defined. We conducted genomic surveillance of 3492 children with diarrhea in two pediatric hospitals in Zhejiang Province in 2017, 2018, and 2021, combining culture, whole‐genome sequencing, and source‐attribution ...
Dongyan Shao   +9 more
wiley   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

open access: yesiNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang   +9 more
wiley   +1 more source

Novel Target for Pathogenic Leptospira Detection via Colorimetric Loop‐Mediated Isothermal Amplification (LAMP): Development, Validation, and Comparative Analysis

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
A novel colorimetric LAMP assay targeting the org‐hp gene was developed for rapid Leptospira detection. The assay is performed in a simple water bath at 65°C for 90 min, and results can be interpreted by a color change visible to the naked eye. This method provides a sensitive, specific, and field‐adaptable diagnostic tool for use in resource‐limited ...
Peyman Ghoraishizadeh   +9 more
wiley   +1 more source

Multi-metal contamination shapes abundance, co-occurrence, and mobility potential of resistance and virulence genes in mining-impacted soils. [PDF]

open access: yesInfect Med (Beijing)
Zhang Q   +13 more
europepmc   +1 more source

Microbial burden of periodontal diseases and its clinical application: The stage, grade, and furcation matter

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontal diseases are associated with dysbiotic oral microbial communities, but clinically applicable measures that reflect microbial burden across disease severity and progression remain limited. This study aimed to assess the oral microbial burden of periodontal diseases by evaluating salivary and subgingival lipopolysaccharide
Anbo Dong   +8 more
wiley   +1 more source

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