Results 311 to 320 of about 5,329,833 (353)
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DNA topology and bacterial virulence gene regulation
Trends in Microbiology, 1993The topology of bacterial DNA varies in response to extracellular environmental stimuli, providing a possible mechanism for environmental control of gene expression during bacterial pathogenesis. The contribution of DNA topology to the control of transcription is complex, but an appreciation of the distinction between local and global DNA topological ...
C J, Dorman, N, Ní Bhriain
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Virulence gene regulation in vivo
Trends in Microbiology, 2001Vibrio cholerae, the causative agent of epidemic cholera, must coordinate the expression of its virulence genes to produce disease. The most well defined virulence factors are the cholera toxin (CT) and the toxin co-regulated pilus (TCP), which are regulated by ToxR, TcpP and ToxT.
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CRISPR Gene Editing of Virulent Bacteriophage ICP1
Cold Spring Harbor Protocols, 2023Tools for site-directed mutagenesis of virulent bacteriophages (phages; viruses of bacteria) have traditionally lagged those for bacteria, hindering their study. CRISPR gene editing represents a new and highly efficient method for editing virulent phage genomes.
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Virulence Gene Regulation in Escherichia coli
EcoSal Plus, 2006Escherichia coli causes three types of illnesses in humans: diarrhea, urinary tract infections, and meningitis in newborns. The acquisition of virulence-associated genes and the ability to properly regulate these, often horizontally transferred, loci distinguishes pathogens from the normally harmless commensal E ...
Jay L, Mellies, Alex M S, Barron
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Defining Virulence Genes in the Dimorphic Fungi
Annual Review of Microbiology, 2006Most dimorphic fungal pathogens cause respiratory disease in mammals and must therefore possess virulence mechanisms to combat and overcome host pulmonary defenses. Over the past decade, advances in genetic tools have made it possible to investigate the basis of dimorphic fungal pathogenesis at the molecular level. Gene disruptions and RNA interference
Chad A, Rappleye, William E, Goldman
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[Virulence gene of H. pylori].
Nihon rinsho. Japanese journal of clinical medicine, 2001H. pylori is a well-recognized pathogen that infects up to 50% of humans in the world. H. pylori lives for decades in the hostile environment of the human stomach. H. pylori is closely associated with histologic gastritis, gastric ulceration, duodenal ulceration, gastric cancer and MALT lymphoma.
T, Sugiyama +3 more
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Agrobacterium virulence gene induction.
Methods in molecular biology (Clifton, N.J.), 2006The ability of Agrobacterium to transform plants and other organisms is under highly regulated genetic control. Two Virulence (Vir) proteins, VirA and VirG, function as a two-component regulatory system to sense particular phenolic compounds synthesized by wounded plant tissues.
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Clinical cases, drug resistance, and virulence genes profiling in Uropathogenic Escherichia coli
Journal of Applied Genetics, 2020Ali Hozzari +4 more
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Virulence gene regulation in Bordetella
2013Bordetella species cause respiratory infections in mammals. Their master regulatory system BvgAS controls expression of at least three distinct phenotypic phases in response to environmental cues. The Bvg+ phase is necessary and sufficient for respiratory infection while the Bvg- phase is required for survival ex vivo.
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Expression of Virulence Genes in Candida Albicans
2005The analysis of virulence gene expression patterns during infection gives insights into regulatory adaptation mechanisms of microbial pathogens in various host niches.The establishment of an in vivo expression technology for C. albicans allows us to investigate at which stage of an infection virulence genes might play a role in the host-pathogen ...
P, Staib +4 more
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