Results 101 to 110 of about 379,610 (192)

Molecular characteristics and pathogenic mechanisms of KPC-3 producing hypervirulent carbapenem-resistant Klebsiella pneumoniae (ST23-K1)

open access: yesFrontiers in Cellular and Infection Microbiology
ObjectiveThis study aimed to comprehensively investigate hypervirulent carbapenem-resistant Klebsiella pneumoniae (CR-hvKP) in the Ningbo region. Importantly, we sought to elucidate its molecular characteristics and pathogenic mechanisms.
Yanye Tu   +4 more
doaj   +1 more source

Verfahren zur Herstellung pharmazeutischer Plasmid-DNA [PDF]

open access: yes, 2008
Voß C. Processes for the production of pharmaceutical grade plasmid DNA. Bielefeld (Germany): Bielefeld University; 2008.Plasmid DNA is currently used in gene therapy and genetic vaccination as a vector system for the delivery of therapeutic genes ...
Voß, Carsten
core  

Parasite variation and the evolution of virulence in a Daphnia-microparasite system [PDF]

open access: yes, 2008
Understanding genetic relationships amongst the life-history traits of parasites is crucial for testing hypotheses on the evolution of virulence. This study therefore examined variation between parasite isolates (the bacterium Pasteuria ramosa) from the ...
Little, T. J., Chadwick, W., Watt, K.
core   +1 more source

Examination of plasmid stability in a recombinant organism used in continuous fermentation [PDF]

open access: yes, 1988
The gene for the enzyme D-GPA dehalogenase has been cloned into a multi-copy plasmid to produce the vector pTB316. It was transformed into two strains of Pseu- domonas putida , AJl-23 and NCIB11767 in the hope of increasing production of this enzyme. The
O'Neill, Mary P.
core  

Analysis of chromosomal involvement in Yersinia pestis virulence plasmid expression [PDF]

open access: yes, 1993
Virulence plasmid expression in the Yersinia has been shown to vary depending upon which species harbors the virulence plasmid suggesting that chromosomal regulation may in some way be involved. In this study, fertility plasmid expression in Y.
Birrer, Teresa Sandelin
core   +1 more source

Emergence of KPC-2 and NDM-13-coproducing carbapenem-resistant hypervirulent Klebsiella pneumoniae with high-risk sequence type ST11

open access: yesFrontiers in Microbiology
BackgroundCarbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) co-producing KPC and NDM poses serious threats to public health. This study aimed to elucidate the molecular mechanisms underlying the resistance and virulence of a clinical CR ...
Jia Tao   +12 more
doaj   +1 more source

Antibiotic residues and R-plasmid selection: are in vitro methods good models? [PDF]

open access: yes, 1987
Three clones of E. coli, one of which was harbouring a tetracycline resistance plasmid were inoculated together into the stomach of axenic mice. Without antibiotic selective pressure, the R-Plasmid bearing strain became dominant in the faeces of mice ...
Lumeau, Solange, Corpet, Denis E.
core  

Genomic insights into the evolution and mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae co-harboring bla KPC and bla NDM: implications for public health threat mitigation

open access: yesAnnals of Clinical Microbiology and Antimicrobials
Background Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) co-producing bla KPC and bla NDM poses a serious threat to public health.
Qian Wang   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy