Results 201 to 210 of about 2,401,730 (258)

Standardized Research Methodology for Akkermansia muciniphila: Multi‐Omics Integration, Functional Evaluation, and Clinical Translation Pathways

Gut Medicine, EarlyView.
ABSTRACT Background Akkermansia muciniphila has emerged as a leading next‐generation beneficial microbe candidate in gut microbiome research, linked to host metabolic homeostasis, mucosal immune regulation, and intestinal barrier integrity. However, marked methodological heterogeneity in isolation and culture conditions, detection and quantification ...
Jiaxin Chen, Mantang Qiu
wiley   +1 more source

The rsmS (ybaM) mutation causes bypass suppression of the RsmAB post-transcriptional virulence regulation system in enterobacterial phytopathogens. [PDF]

Sci Rep, 2019
Monson RE, Apagyi K, Bowden SD, Simpson N, Williamson NR, Cubitt MF, Harris S, Toth IK, Salmond GPC.   +8 more
europepmc   +1 more source

Metagenomic and culture‐based insights into host and plasmid contexts of high‐risk ARGs in poultry farm environments

iMetaOmics, EarlyView.
Shotgun metagenomics and culture‐based isolate genomics revealed position‐associated high‐risk antibiotic resistance genes (ARGs) signals across poultry manure piles and surrounding soils. Culture‐confirmed Enterobacteriaceae and IncHI2A‐related blaNDM‐5 plasmid backgrounds further highlight priority host‐ARG‐plasmid contexts for farm antimicrobial ...
Yaling Wang, Lianwei Ye, Linan He, Zhenlong Wu, Yiwen Yang, Sheng Chen   +5 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent Klebsiella pneumoniae

iMeta, EarlyView.
Transient exposure to ampicillin results in restructuring of microbiota to favor oxygen‐tolerant bacteria, whereas osmotic laxative perturbation preserves Bacteriodota. Ampicillin‐ but not laxative‐exposed environment favors establishment of rmpA phase variants that lost hypermucoviscosity but short‐chain fatty acids present in the laxative‐exposed gut
Carey Lim, Jialing Zheng, Guoxiang Cheam, Melvin Yong, Hanrong Chen, Andrew Ting, Yahua Chen, Qingqing Wang, Niranjan Nagarajan, Yunn‐Hwen Gan   +9 more
wiley   +1 more source

Canine Distemper Virus Research in China and Future Directions for Conservation 中国犬瘟热病毒研究现状与保护策略展望

Integrative Conservation, EarlyView.
ABSTRACT Canine distemper is a highly contagious, severe disease caused by the canine distemper virus (CDV). With a worldwide distribution and ever‐expanding list of susceptible hosts, CDV poses a growing risk for many threatened wildlife species, both in captivity and their native habitats. As a megadiverse country, China is home to myriad endemic and
Aliana C. Norris, Xiaoxu Peng, Hua Zhong, Joseph P. Lambert, Philip Riordan   +4 more
wiley   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

iNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang, Yajuan Wu, Huayang Sheng, Shouhong Jiang, Jinping Cheng, Ye Kuang, Miao Liu, Lei Feng, Yanan Sun, Jinzhi Duan   +9 more
wiley   +1 more source

Association of IFN‐γ +874 T/A Polymorphism With COVID‐19 Susceptibility, Severity, and Inflammatory Response: A Case–Control Study From Southern Iran

Journal of Clinical Laboratory Analysis, EarlyView.
Graphical abstract illustrating the association between IFN‐γ +874 T/A polymorphism and COVID‐19 outcomes. TA and AA genotypes are linked to increased susceptibility, higher inflammatory markers (notably IL‐6), greater disease severity, and longer hospitalization.
Nasir Arefinia, Bahman Aghcheli, Seyed Mohammad Ali Hashemi, Zohreh‐al‐sadat Ghoreshi, Emad Behboudi   +4 more
wiley   +1 more source

Zinc‐stabilized stannous fluoride modulates the periodontal microbiome, reducing Fusobacteria, key Gram‐negative species, and overall inflammation within an experimental gingivitis clinical trial

Journal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the effects of a dentifrice containing stannous fluoride stabilized with zinc phosphate on subgingival microbiome composition and clinical inflammation during experimental gingivitis, compared with a sodium fluoride control. Methods This investigation was conducted as a secondary analysis of a randomized,
Kristopher A. Kerns, Allison A. Naumann, Lay Y. Soon, Erik L. Hendrickson, Abdelahhad Barbour, Dandan Chen, Harsh M. Trivedi, Michael Glogauer, Jeffrey S. McLean   +8 more
wiley   +1 more source

Periodontitis and gastric disorders: Systematic review and meta‐analysis of functional dyspepsia and Helicobacter pylori gastritis

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis has been associated with other systemic inflammatory diseases, such as cardiovascular disease, diabetes mellitus, and rheumatoid arthritis; through the translocation of oral bacteria and local inflammatory mediators systemically.
Hadeel Mohammed Abbood, Jasim Mohammed Abbood, Ekin Yay‐Kus, Iain L. C. Chapple   +3 more
wiley   +1 more source