Results 221 to 230 of about 2,401,730 (258)

Histone Acetylation Dynamics Regulate Fungal Development, Pathogenicity, and Mycotoxin Biosynthesis. [PDF]

J Fungi (Basel)
Gong C, Li Z, Xu D, Sun D, Wang Z, Du X, Zhang Y, Qi X.   +7 more
europepmc   +1 more source

z‐VAD‐FMK triggers macrophage necroptosis during mycobacterial infection via a non‐canonical off‐target mechanism

mLife, EarlyView.
Abstract Macrophages are the predominant cell type infected by Mycobacterium tuberculosis (Mtb) in tuberculosis (TB). Death of Mtb‐infected macrophages promotes tissue pathology and releases Mtb to infect other cells, suggesting that inhibiting the death of Mtb‐infected macrophages could be an adjunctive treatment of TB.
Rong Hu, Pei Li, Jie Han, Jiamin Huang, Guoyi Huang, Xiuju Jiang, Daniel Pfau, Guobao Li, Yi‐Nan Gong, Carl F. Nathan, Li Zhang   +10 more
wiley   +1 more source

Reactive Oxygen Species-Responsive Signaling Networks and Oxidative Stress Adaptation in Critical Priority Fungal Pathogens. [PDF]

J Fungi (Basel)
George RB, Pradeep HG, Adikaledath Mana N, Raj N, Praveen P, Harish RP, Mahesh N, Renuka D, Nair BG, Kumar GB, Haripriyan J.   +10 more
europepmc   +1 more source

ISAba1‐mediated crp‐osmC amplification enhances host‐associated fitness in Acinetobacter baumannii

mLife, EarlyView.
Abstract Acinetobacter baumannii is a pathogen, highly adaptable to both hospital‐ and host‐associated environments. Understanding the genetic mechanisms underlying its adaptability is critical for controlling its persistence. Our study identified the crp‐osmC gene cluster, flanked by ISAba1 elements, as a significant genetic structure undergoing ...
Da‐Wei Wei, Jiangqing Huang, Hailing Fang, Xinyu Wang, Gang Zhang, Chao Wang, Yuqin Song, Jie Feng   +7 more
wiley   +1 more source

Two-Component System as Drug Target: Is It a Bandwagon or a Breakthrough? [PDF]

Drug Dev Res
Haldiya A, Kain H, Kumari P, Srivastava VK, Sharma V, Kothari SL, Kaushik S.   +6 more
europepmc   +1 more source

Does bigger mean sicker? A systematic review and meta‐analysis of the intraspecific relationship between host body size and parasite infection across vertebrate taxa

Oikos, EarlyView.
Elucidating the determinants of parasite infection levels of individuals within a population is a basic but important step for understanding the roles of parasites in natural systems. Among intraspecific studies on vertebrate hosts and metazoan parasites, host body size (length/mass) is probably the most frequently reported factor determining parasite ...
Ryota Hasegawa, Daniela de Angeli Dutra, Bronwen Presswell, Jerusha Bennett, Cameron McDougall, Katherine E. Buschang, Xuhong Chai, Robert Poulin   +7 more
wiley   +1 more source

Phenotypic Effects of a Small Molecule CpxA Phosphatase Inhibitor on Uropathogenic Escherichia coli. [PDF]

ACS Infect Dis
Stoorza AM, Carlson EE, Duerfeldt AS.
europepmc   +1 more source

Biosurfactant production by Pseudomonas aeruginosa isolated from mining waste: From genomic analysis to development of a polymeric composite for removal of hexavalent chromium

Polymer International, EarlyView.
Biosurfactant was produced by Pseudomonas aeruginosa using andiroba waste from Amazonia. A biosurfactant–alginate composite (Alg/BioS) was successfully synthesized via ionotropic gelation, and achieved up to 70% Cr6+ removal from water. Abstract Environmental contamination by heavy metals represents a significant challenge due to their persistence in ...
Paulo Diniz Austriaco, Emilly Cruz da Silva, Glenda Sores Gomes, Joane Almeida Alves, Amanda Vidal, Leandro Argolo, Rafaela Ribeiro, Luciana Souza, José Augusto Pires Bitencourt, Leonardo Brasil Felipe, Leonie Asfora Sarubbo, Sidnei Cerqueira dos Santos   +11 more
wiley   +1 more source

Disruption of Functional Membrane Microdomains Enhances Methicillin-Resistant <i>Staphylococcus aureus</i> Pathogenesis via Hyperexpression of Hemolysins. [PDF]

Vet Sci
Jin B, Wang C, Liu T, Dong P, Wang X, Yang X, Yuan D, Yang F.   +7 more
europepmc   +1 more source

Redefining Acne as a Distinct Inflammatory Disease: Acne Is Not an Aesthetic Issue

JEADV Clinical Practice, EarlyView.
Jean Paul Claudel, Fabienne Ballanger, Nicole Auffret, Marie‐Thérèse Leccia, Brigitte Dréno   +4 more
wiley   +1 more source