Results 131 to 140 of about 5,926,013 (258)

Characterization of the virus-host RNA-RNA interactome across important human pathogenic RNA viruses.

PLoS Pathogens
Viruses make extensive use of host cell machinery, however, most systematic studies of virus-host interactions focused on proteins with less attention to nucleic acids.
Nkerorema Djodji Damas, Stefan E Seemann, Rui Costa, Janina Krambrich, Nicolas Fossat, Lizandro R Rivera-Rangel, Ulrik Fahnøe, Louise Nielsen, Jan Gorodkin, Jens Bukh, Troels K H Scheel   +10 more
doaj   +1 more source

Virus-host interaction analysis in colorectal cancer identifies core virus network signature and small molecules. [PDF]

Comput Struct Biotechnol J, 2022
A V S SK, Sinha S, Donakonda S.
europepmc   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

The role of VIF in overcoming the APOBEC3G block to HIV-1 replication [PDF]

This project focuses on the Virus Infectivity Factor protein of HIV-1 and its relief of the block to virus replication exerted by the APOBEC3G component of the innate immune response.
Kulkarni, Anurag
core  

Integrated computational and experimental analysis of host-virus interaction systems [PDF]

, 2016
Host-virus systems biology seeks to elucidate the complex interactions between a virus and its host, and to determine the downstream consequences of these interactions for the host. Traditional studies of host-virus interactions, conducted one-at-a-time,
Garamszegi, Sara
core   +1 more source

Emerging translation strategies during virus-host interaction. [PDF]

Wiley Interdiscip Rev RNA, 2021
Hoang HD, Neault S, Pelin A, Alain T.
europepmc   +1 more source

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

Advanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury

Advanced Science, EarlyView.
This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang, Jihong Jiang, Huanxin Yin, Chunyan Liu, Hongjun Huang, Yan Luo, Minmin Zhu, Qiuyun Wang   +7 more
wiley   +1 more source

Roles of Non-Coding RNAs in Virus-Host Interaction About Pathogenesis of Hand-Foot-Mouth Disease. [PDF]

Curr Microbiol, 2022
Chen W, Li J, Li J, Zhang J, Zhang J.
europepmc   +1 more source

Battery‐Inspired Electrochemical Synapses for Neuromorphic Applications

Advanced Science, EarlyView.
Battery‐ion‐inspired synaptic devices integrate diverse electrolyte systems (solid, ion‐gel, liquid) with transition metal oxides, two‐dimensional materials, and organic channels to regulate ion‐electron coupling. By tailoring ion transport and host interactions, these platforms enable controllable plasticity and energy‐efficient implementations for ...
Won Woo Lee, SeongCheol Jang, Wangmyung Choi, Jaewon Park, Jaehyun Hur, Hocheon Yoo, Hyun‐Suk Kim   +6 more
wiley   +1 more source